Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2075641..2075786 Replicon chromosome
Accession NZ_CP098352
Organism Klebsiella pneumoniae strain 52977_A1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2075677..2075779 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2075641..2075786 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB671_RS10000 (NB671_10000) 2070771..2072831 + 2061 WP_004151449.1 oligopeptidase B -
NB671_RS10005 (NB671_10005) 2072835..2073494 - 660 WP_002911407.1 exodeoxyribonuclease X -
NB671_RS10010 (NB671_10010) 2073573..2073803 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NB671_RS10015 (NB671_10015) 2073916..2074290 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NB671_RS10020 (NB671_10020) 2074294..2075163 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NB671_RS10025 (NB671_10025) 2075180..2075518 + 339 WP_002911404.1 YebY family protein -
- 2075641..2075786 - 146 - - Antitoxin
- 2075677..2075779 + 103 - - Toxin
NB671_RS10030 (NB671_10030) 2076154..2076297 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NB671_RS10035 (NB671_10035) 2076402..2077370 - 969 WP_004151446.1 VirK/YbjX family protein -
NB671_RS10040 (NB671_10040) 2077527..2078180 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
NB671_RS10045 (NB671_10045) 2078177..2078368 - 192 WP_002911395.1 YebW family protein -
NB671_RS10050 (NB671_10050) 2078466..2078705 - 240 WP_002911393.1 YebV family protein -
NB671_RS10055 (NB671_10055) 2078821..2080254 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T247543 NZ_CP098352:2075677-2075779 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT247543 NZ_CP098352:c2075786-2075641 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References