Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2074616..2074761 Replicon chromosome
Accession NZ_CP098350
Organism Klebsiella pneumoniae strain 52980_A4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2074652..2074754 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2074616..2074761 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB670_RS09985 (NB670_09985) 2069746..2071806 + 2061 WP_004151449.1 oligopeptidase B -
NB670_RS09990 (NB670_09990) 2071810..2072469 - 660 WP_002911407.1 exodeoxyribonuclease X -
NB670_RS09995 (NB670_09995) 2072548..2072778 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NB670_RS10000 (NB670_10000) 2072891..2073265 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NB670_RS10005 (NB670_10005) 2073269..2074138 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NB670_RS10010 (NB670_10010) 2074155..2074493 + 339 WP_002911404.1 YebY family protein -
- 2074616..2074761 - 146 - - Antitoxin
- 2074652..2074754 + 103 - - Toxin
NB670_RS10015 (NB670_10015) 2075129..2075272 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NB670_RS10020 (NB670_10020) 2075377..2076345 - 969 WP_004151446.1 VirK/YbjX family protein -
NB670_RS10025 (NB670_10025) 2076502..2077155 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
NB670_RS10030 (NB670_10030) 2077152..2077343 - 192 WP_002911395.1 YebW family protein -
NB670_RS10035 (NB670_10035) 2077441..2077680 - 240 WP_002911393.1 YebV family protein -
NB670_RS10040 (NB670_10040) 2077796..2079229 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T247527 NZ_CP098350:2074652-2074754 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT247527 NZ_CP098350:c2074761-2074616 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References