Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2055200..2055345 Replicon chromosome
Accession NZ_CP098343
Organism Klebsiella pneumoniae strain 53009_G1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2055236..2055338 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2055200..2055345 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB668_RS09825 (NB668_09825) 2050330..2052390 + 2061 WP_032422099.1 oligopeptidase B -
NB668_RS09830 (NB668_09830) 2052394..2053053 - 660 WP_002911407.1 exodeoxyribonuclease X -
NB668_RS09835 (NB668_09835) 2053132..2053362 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NB668_RS09840 (NB668_09840) 2053475..2053849 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NB668_RS09845 (NB668_09845) 2053853..2054722 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NB668_RS09850 (NB668_09850) 2054739..2055077 + 339 WP_002911404.1 YebY family protein -
- 2055200..2055345 - 146 - - Antitoxin
- 2055236..2055338 + 103 - - Toxin
NB668_RS09855 (NB668_09855) 2055713..2055856 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NB668_RS09860 (NB668_09860) 2055961..2056929 - 969 WP_004151446.1 VirK/YbjX family protein -
NB668_RS09865 (NB668_09865) 2057086..2057739 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
NB668_RS09870 (NB668_09870) 2057736..2057927 - 192 WP_002911395.1 YebW family protein -
NB668_RS09875 (NB668_09875) 2058025..2058264 - 240 WP_002911393.1 YebV family protein -
NB668_RS09880 (NB668_09880) 2058380..2059813 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T247485 NZ_CP098343:2055236-2055338 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT247485 NZ_CP098343:c2055345-2055200 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References