Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2055123..2055268 Replicon chromosome
Accession NZ_CP098340
Organism Klebsiella pneumoniae strain 53015_G7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2055159..2055261 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2055123..2055268 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB667_RS09825 (NB667_09825) 2050253..2052313 + 2061 WP_032422099.1 oligopeptidase B -
NB667_RS09830 (NB667_09830) 2052317..2052976 - 660 WP_002911407.1 exodeoxyribonuclease X -
NB667_RS09835 (NB667_09835) 2053055..2053285 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NB667_RS09840 (NB667_09840) 2053398..2053772 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NB667_RS09845 (NB667_09845) 2053776..2054645 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NB667_RS09850 (NB667_09850) 2054662..2055000 + 339 WP_002911404.1 YebY family protein -
- 2055123..2055268 - 146 - - Antitoxin
- 2055159..2055261 + 103 - - Toxin
NB667_RS09855 (NB667_09855) 2055636..2055779 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NB667_RS09860 (NB667_09860) 2055884..2056852 - 969 WP_004151446.1 VirK/YbjX family protein -
NB667_RS09865 (NB667_09865) 2057009..2057662 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
NB667_RS09870 (NB667_09870) 2057659..2057850 - 192 WP_002911395.1 YebW family protein -
NB667_RS09875 (NB667_09875) 2057948..2058187 - 240 WP_002911393.1 YebV family protein -
NB667_RS09880 (NB667_09880) 2058303..2059736 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T247470 NZ_CP098340:2055159-2055261 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT247470 NZ_CP098340:c2055268-2055123 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References