Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2114938..2115083 Replicon chromosome
Accession NZ_CP098338
Organism Klebsiella pneumoniae strain 53022_J1

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2114974..2115076 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2114938..2115083 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB666_RS10250 (NB666_10250) 2110068..2112128 + 2061 WP_004151449.1 oligopeptidase B -
NB666_RS10255 (NB666_10255) 2112132..2112791 - 660 WP_002911407.1 exodeoxyribonuclease X -
NB666_RS10260 (NB666_10260) 2112870..2113100 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NB666_RS10265 (NB666_10265) 2113213..2113587 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NB666_RS10270 (NB666_10270) 2113591..2114460 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NB666_RS10275 (NB666_10275) 2114477..2114815 + 339 WP_002911404.1 YebY family protein -
- 2114938..2115083 - 146 - - Antitoxin
- 2114974..2115076 + 103 - - Toxin
NB666_RS10280 (NB666_10280) 2115451..2115594 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NB666_RS10285 (NB666_10285) 2115699..2116667 - 969 WP_004151446.1 VirK/YbjX family protein -
NB666_RS10290 (NB666_10290) 2116824..2117477 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
NB666_RS10295 (NB666_10295) 2117474..2117665 - 192 WP_002911395.1 YebW family protein -
NB666_RS10300 (NB666_10300) 2117763..2118002 - 240 WP_002911393.1 YebV family protein -
NB666_RS10305 (NB666_10305) 2118118..2119551 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T247454 NZ_CP098338:2114974-2115076 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT247454 NZ_CP098338:c2115083-2114938 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References