Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2103666..2103811 Replicon chromosome
Accession NZ_CP098335
Organism Klebsiella pneumoniae strain 53023_J2

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2103702..2103804 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2103666..2103811 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB665_RS10205 (NB665_10205) 2098796..2100856 + 2061 WP_004151449.1 oligopeptidase B -
NB665_RS10210 (NB665_10210) 2100860..2101519 - 660 WP_002911407.1 exodeoxyribonuclease X -
NB665_RS10215 (NB665_10215) 2101598..2101828 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NB665_RS10220 (NB665_10220) 2101941..2102315 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NB665_RS10225 (NB665_10225) 2102319..2103188 + 870 WP_004151447.1 copper homeostasis membrane protein CopD -
NB665_RS10230 (NB665_10230) 2103205..2103543 + 339 WP_002911404.1 YebY family protein -
- 2103666..2103811 - 146 - - Antitoxin
- 2103702..2103804 + 103 - - Toxin
NB665_RS10235 (NB665_10235) 2104179..2104322 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NB665_RS10240 (NB665_10240) 2104427..2105395 - 969 WP_004151446.1 VirK/YbjX family protein -
NB665_RS10245 (NB665_10245) 2105552..2106205 + 654 WP_002911396.1 protein-serine/threonine phosphatase -
NB665_RS10250 (NB665_10250) 2106202..2106393 - 192 WP_002911395.1 YebW family protein -
NB665_RS10255 (NB665_10255) 2106491..2106730 - 240 WP_002911393.1 YebV family protein -
NB665_RS10260 (NB665_10260) 2106846..2108279 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T247438 NZ_CP098335:2103702-2103804 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT247438 NZ_CP098335:c2103811-2103666 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References