Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 54180..54699 Replicon plasmid p59174-57.6
Accession NZ_CP098332
Organism Citrobacter freundii strain 59174

Toxin (Protein)


Gene name parE Uniprot ID A0A9E7BHM1
Locus tag NB664_RS26070 Protein ID WP_047389778.1
Coordinates 54415..54699 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID A0A9E7BH21
Locus tag NB664_RS26065 Protein ID WP_047389775.1
Coordinates 54180..54422 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB664_RS27550 49856..49951 + 96 WP_000609145.1 DinQ-like type I toxin DqlB -
NB664_RS26050 (NB664_26050) 50137..50379 - 243 WP_052132603.1 hypothetical protein -
NB664_RS26055 (NB664_26055) 50778..51800 - 1023 WP_001567660.1 IS110 family transposase -
NB664_RS26060 (NB664_26060) 52159..53181 + 1023 WP_001567660.1 IS110 family transposase -
NB664_RS26065 (NB664_26065) 54180..54422 + 243 WP_047389775.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
NB664_RS26070 (NB664_26070) 54415..54699 + 285 WP_047389778.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NB664_RS26075 (NB664_26075) 54831..55058 - 228 WP_047389780.1 plasmid partition protein ParG -
NB664_RS26080 (NB664_26080) 55097..55717 - 621 WP_047389782.1 ParA family partition ATPase -
NB664_RS26085 (NB664_26085) 55868..56170 - 303 WP_052132604.1 hypothetical protein -
NB664_RS26090 (NB664_26090) 56481..57176 + 696 WP_047389784.1 IS6-like element ISEas1 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..57636 57636
- inside IScluster/Tn - - 50778..57176 6398


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-88)

Antitoxin

Antitoxin ParD

(1-64)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10965.46 Da        Isoelectric Point: 6.2103

>T247432 WP_047389778.1 NZ_CP098332:54415-54699 [Citrobacter freundii]
VYKLTERAADDFAGIYDYTLLKFGEAQADHYTDALEAFFETLAGMPDMGRDYHAVSGVMRIEFQRHAIFYTVRDTDILIA
RILHQQMNHKRHLL

Download         Length: 285 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 8949.09 Da        Isoelectric Point: 7.0142

>AT247432 WP_047389775.1 NZ_CP098332:54180-54422 [Citrobacter freundii]
MARTTSVTIGEQLDSFISRLIDSGRYGSASEVMRSALRLLEQQETNDEVVRQAVITGLESGESSLSLRDIAEKRKLRHRV

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References