Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3834443..3835103 Replicon chromosome
Accession NZ_CP098325
Organism Leclercia adecarboxylata strain kcgeb_e1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag NB069_RS18055 Protein ID WP_250585783.1
Coordinates 3834443..3834856 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag NB069_RS18060 Protein ID WP_039029834.1
Coordinates 3834837..3835103 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB069_RS18035 (NB069_18035) 3830446..3832179 - 1734 WP_250585775.1 single-stranded-DNA-specific exonuclease RecJ -
NB069_RS18040 (NB069_18040) 3832185..3832898 - 714 WP_250585777.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
NB069_RS18045 (NB069_18045) 3832920..3833816 - 897 WP_250585779.1 site-specific tyrosine recombinase XerD -
NB069_RS18050 (NB069_18050) 3833917..3834438 + 522 WP_250585781.1 flavodoxin FldB -
NB069_RS18055 (NB069_18055) 3834443..3834856 - 414 WP_250585783.1 protein YgfX Toxin
NB069_RS18060 (NB069_18060) 3834837..3835103 - 267 WP_039029834.1 FAD assembly factor SdhE Antitoxin
NB069_RS18065 (NB069_18065) 3835407..3836387 + 981 WP_250585786.1 tRNA-modifying protein YgfZ -
NB069_RS18070 (NB069_18070) 3836478..3837137 - 660 WP_250585788.1 hemolysin III family protein -
NB069_RS18075 (NB069_18075) 3837303..3837614 - 312 WP_250585790.1 N(4)-acetylcytidine aminohydrolase -
NB069_RS18080 (NB069_18080) 3837667..3838398 + 732 WP_250589541.1 MurR/RpiR family transcriptional regulator -
NB069_RS18085 (NB069_18085) 3838513..3839946 + 1434 WP_250585792.1 6-phospho-beta-glucosidase BglA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16193.01 Da        Isoelectric Point: 11.1911

>T247417 WP_250585783.1 NZ_CP098325:c3834856-3834443 [Leclercia adecarboxylata]
VVLWQSDLRVSWRSQWMSLLLHGLVAAFILLMPWPLSYTPLWLILLSLVVFDSVRSQRRINARQGEIKLFMDSRLHWLGS
EWEIVGTPWMLNSGMMLRLRKSAGQRCHHLWLAADSMDEGEWRDLRRMISHQPTQGR

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10568.01 Da        Isoelectric Point: 4.5242

>AT247417 WP_039029834.1 NZ_CP098325:c3835103-3834837 [Leclercia adecarboxylata]
MDINNKARIHWACRRGMRELDISIMPFFEYEYDSLSDEDKQLFIRLLENDDPDLFNWLMNHGEPADTELQRMVLLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References