Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) chpSB/PRK09812-ChpS
Location 448670..449265 Replicon chromosome
Accession NZ_CP098325
Organism Leclercia adecarboxylata strain kcgeb_e1

Toxin (Protein)


Gene name chpB Uniprot ID -
Locus tag NB069_RS02125 Protein ID WP_250587354.1
Coordinates 448915..449265 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name chpS Uniprot ID -
Locus tag NB069_RS02120 Protein ID WP_250587352.1
Coordinates 448670..448921 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB069_RS02110 (NB069_02110) 444337..448113 + 3777 WP_250587350.1 autotransporter assembly complex protein TamB -
NB069_RS02115 (NB069_02115) 448116..448460 + 345 WP_039028479.1 gamma-glutamylcyclotransferase -
NB069_RS02120 (NB069_02120) 448670..448921 + 252 WP_250587352.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
NB069_RS02125 (NB069_02125) 448915..449265 + 351 WP_250587354.1 type II toxin-antitoxin system ChpB family toxin Toxin
NB069_RS02130 (NB069_02130) 449371..449898 - 528 WP_250587356.1 inorganic diphosphatase -
NB069_RS02135 (NB069_02135) 450208..451164 + 957 WP_032616231.1 galactofuranose ABC transporter substrate-binding protein YtfQ -
NB069_RS02140 (NB069_02140) 451269..452771 + 1503 WP_250587358.1 sugar ABC transporter ATP-binding protein -
NB069_RS02145 (NB069_02145) 452782..453807 + 1026 WP_250587360.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-116)

Antitoxin

SpoVT-AbrB domain

(6-49)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12516.50 Da        Isoelectric Point: 6.9497

>T247407 WP_250587354.1 NZ_CP098325:448915-449265 [Leclercia adecarboxylata]
MVKARGFERGDIVRVRFSPSSGHEQQGEGRPALVLSVSAFNQLGMVLVAPITQGGNFARYAGFCVPVSCEEGDVQGVILV
NQIRMMDLKARQAIKVAVATDDVVQDALMRLQAIVD

Download         Length: 351 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 8916.28 Da        Isoelectric Point: 4.0463

>AT247407 WP_250587352.1 NZ_CP098325:448670-448921 [Leclercia adecarboxylata]
MRITIKKWGNSAGVVIPGVVMLELNMQVGQSMDAQVVDNQLVLTPVSKGYSLEALLAQCDMAAPEIGEDALWGKSDPTGN
EVW

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References