Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/Txe-RelB
Location 423829..424336 Replicon chromosome
Accession NZ_CP098324
Organism Rickettsia conorii subsp. raoultii strain BIME

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag NBT09_RS02315 Protein ID WP_064462994.1
Coordinates 424073..424336 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID H8K421
Locus tag NBT09_RS02310 Protein ID WP_014391803.1
Coordinates 423829..424080 (+) Length 84 a.a.

Genomic Context

NBT09_RS02310NBT09_RS02315NBT09_RS02320NBT09_RS02325NBT09_RS02330NBT09_RS02275NBT09_RS02280NBT09_RS02285NBT09_RS02290NBT09_RS02295NBT09_RS02300NBT09_RS02305NBT09_RS02335NBT09_RS02340
Location: 423829..424080 (252 bp)
Type: Antitoxin
Protein ID: WP_014391803.1
Location: 424073..424336 (264 bp)
Type: Toxin
Protein ID: WP_064462994.1
Location: 424396..425601 (1206 bp)
Type: Others
Protein ID: WP_064462992.1
Location: 425752..426408 (657 bp)
Type: Others
Protein ID: WP_064462990.1
Location: 426405..427799 (1395 bp)
Type: Others
Protein ID: WP_064462988.1
Location: 418997..420064 (1068 bp)
Type: Others
Protein ID: WP_250720035.1
Location: 420131..420349 (219 bp)
Type: Others
Protein ID: WP_232218745.1
Location: 420380..420715 (336 bp)
Type: Others
Protein ID: Protein_453
Location: 420782..421081 (300 bp)
Type: Others
Protein ID: WP_064463000.1
Location: 421306..421905 (600 bp)
Type: Others
Protein ID: WP_064462998.1
Location: 421925..422680 (756 bp)
Type: Others
Protein ID: WP_250720037.1
Location: 422685..423689 (1005 bp)
Type: Others
Protein ID: WP_250720040.1
Location: 427820..428161 (342 bp)
Type: Others
Protein ID: WP_250720042.1
Location: 428206..428835 (630 bp)
Type: Others
Protein ID: WP_250720045.1
ToxinAntitoxinOther genes
Loading, please wait
Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
NBT09_RS02275 (NBT09_02275)418997..420064-1068WP_250720035.1alanine racemase-
NBT09_RS02280 (NBT09_02280)420131..420349-219WP_232218745.1palindromic element RPE1 domain-containing protein-
NBT09_RS02285 (NBT09_02285)420380..420715-336Protein_453ribose-phosphate diphosphokinase-
NBT09_RS02290 (NBT09_02290)420782..421081-300WP_064463000.1ribose-phosphate pyrophosphokinase-like domain-containing protein-
NBT09_RS02295 (NBT09_02295)421306..421905-600WP_064462998.1phospholipid-binding protein MlaC-
NBT09_RS02300 (NBT09_02300)421925..422680-756WP_250720037.1VacJ family lipoprotein-
NBT09_RS02305 (NBT09_02305)422685..423689-1005WP_250720040.1methyltransferase domain-containing protein-
NBT09_RS02310 (NBT09_02310)423829..424080+252WP_014391803.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
NBT09_RS02315 (NBT09_02315)424073..424336+264WP_064462994.1Txe/YoeB family addiction module toxinToxin
NBT09_RS02320 (NBT09_02320)424396..425601+1206WP_064462992.1pyridoxal phosphate-dependent aminotransferase-
NBT09_RS02325 (NBT09_02325)425752..426408+657WP_064462990.1lysophospholipid acyltransferase family protein-
NBT09_RS02330 (NBT09_02330)426405..427799+1395WP_064462988.1lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase-
NBT09_RS02335 (NBT09_02335)427820..428161-342WP_250720042.1hypothetical protein-
NBT09_RS02340 (NBT09_02340)428206..428835-630WP_250720045.1hypothetical protein-

Associated MGEs

Loading, please wait
MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10571.43 Da        Isoelectric Point: 10.1250

>T247405 WP_064462994.1 NZ_CP098324:424073-424336 [Rickettsia conorii subsp. raoultii]
MIEIEWTLEAAEDLAYWKKYDIKKYERIKLLIKNIQEAPFTGIGKPKPLKHILSGLWSRRINHEHRLIYSVNTKQIIIYN
CRFHYKN

Download         Length: 264 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9521.77 Da        Isoelectric Point: 9.4884

>AT247405 WP_014391803.1 NZ_CP098324:423829-424080 [Rickettsia conorii subsp. raoultii]
MNSISGTSFRKNLSSVLNTVENDHVPYLIKRKNHKNIILLTEEEYESTKETLYLLSNPANANRIKKSIEQAKRGEFAKVN
LDD

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
Loading, please wait
Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

Loading, please wait
Source
ID
Structure
No matching records found

Antitoxin

Loading, please wait
Source
ID
Structure
AlphaFold DBA0A0C2M0P5

References