Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 408696..409277 Replicon chromosome
Accession NZ_CP098247
Organism Oxalobacter aliiformigenes strain BA2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NB636_RS01915 Protein ID WP_269280998.1
Coordinates 408696..408989 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NB636_RS01920 Protein ID WP_269280996.1
Coordinates 408993..409277 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB636_RS01885 (NB636_01880) 404366..405202 + 837 WP_269281008.1 dihydropteroate synthase -
NB636_RS01890 (NB636_01885) 405226..406572 + 1347 WP_269281005.1 phosphoglucosamine mutase -
NB636_RS01905 (NB636_01900) 406912..407958 - 1047 WP_269281003.1 site-specific integrase -
NB636_RS01910 (NB636_01905) 408156..408623 - 468 WP_269281001.1 single-stranded DNA-binding protein -
NB636_RS01915 (NB636_01910) 408696..408989 + 294 WP_269280998.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NB636_RS01920 (NB636_01915) 408993..409277 + 285 WP_269280996.1 putative addiction module antidote protein Antitoxin
NB636_RS01925 (NB636_01920) 409514..410557 - 1044 WP_269280993.1 recombinase RecT -
NB636_RS01930 (NB636_01925) 410568..411470 - 903 WP_269280991.1 YqaJ viral recombinase family protein -
NB636_RS01935 (NB636_01930) 411470..411637 - 168 WP_269280988.1 hypothetical protein -
NB636_RS01940 (NB636_01935) 411707..412063 - 357 WP_269280985.1 hypothetical protein -
NB636_RS01945 (NB636_01940) 412270..412569 + 300 WP_269280982.1 ADP-ribosyl-(dinitrogen reductase) hydrolase -
NB636_RS01950 (NB636_01945) 412562..412882 + 321 WP_269280979.1 hypothetical protein -
NB636_RS01955 (NB636_01950) 413268..413918 - 651 WP_269280978.1 S24 family peptidase -
NB636_RS01960 (NB636_01955) 414018..414224 + 207 WP_269280975.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 406912..455607 48695


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(7-96)

Antitoxin

Uncharacterized protein HI1420

(4-91)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11048.75 Da        Isoelectric Point: 10.0967

>T247352 WP_269280998.1 NZ_CP098247:408696-408989 [Oxalobacter aliiformigenes]
MKYFVEALDSFNDWLGSLRDIRAKVAIVRRIDRAGLGNFGDHKAVGEGVSEMRIDIGQGYRVYYTIRQQRIVFLLCGGNK
VTQSDDIKRAIKLAREV

Download         Length: 294 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10432.87 Da        Isoelectric Point: 5.1409

>AT247352 WP_269280996.1 NZ_CP098247:408993-409277 [Oxalobacter aliiformigenes]
MTIKTTRFDVADFLDSEEAIQEYFRQVVEDGDPDEIVRALGHIARARGMTQLAKDTGLGRESLYKALSEGSKPRFDTIMR
VTKALGLTLTVAQA

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References