Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RHH
Location 317732..318285 Replicon chromosome
Accession NZ_CP098247
Organism Oxalobacter aliiformigenes strain BA2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NB636_RS01485 Protein ID WP_269277900.1
Coordinates 318010..318285 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NB636_RS01480 Protein ID WP_269277898.1
Coordinates 317732..318010 (+) Length 93 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NB636_RS01455 (NB636_01450) 313532..315514 + 1983 WP_269277888.1 acetate--CoA ligase -
NB636_RS01465 (NB636_01460) 315792..316979 - 1188 WP_269277891.1 DUF3596 domain-containing protein -
NB636_RS01470 (NB636_01465) 317139..317327 - 189 WP_269277893.1 hypothetical protein -
NB636_RS01475 (NB636_01470) 317377..317532 - 156 WP_269277895.1 hypothetical protein -
NB636_RS01480 (NB636_01475) 317732..318010 + 279 WP_269277898.1 ribbon-helix-helix domain-containing protein Antitoxin
NB636_RS01485 (NB636_01480) 318010..318285 + 276 WP_269277900.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NB636_RS01490 (NB636_01485) 318363..319337 - 975 WP_269277902.1 hypothetical protein -
NB636_RS01495 (NB636_01490) 319328..319771 - 444 WP_269277904.1 hypothetical protein -
NB636_RS01500 (NB636_01495) 319814..320584 - 771 WP_269277907.1 LexA family transcriptional regulator -
NB636_RS01505 (NB636_01500) 320585..320737 + 153 WP_269277910.1 helix-turn-helix transcriptional regulator -
NB636_RS01510 (NB636_01505) 320734..320931 + 198 WP_269277911.1 hypothetical protein -
NB636_RS01515 (NB636_01510) 320964..321302 + 339 WP_269277914.1 hypothetical protein -
NB636_RS01520 (NB636_01515) 321366..321758 + 393 WP_269295636.1 hypothetical protein -
NB636_RS01525 (NB636_01520) 321755..322354 + 600 WP_269281848.1 hypothetical protein -
NB636_RS01530 (NB636_01525) 322386..322598 - 213 WP_269295637.1 hypothetical protein -
NB636_RS01535 (NB636_01530) 322603..322911 - 309 WP_269281046.1 HigA family addiction module antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-46)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10664.37 Da        Isoelectric Point: 10.4490

>T247351 WP_269277900.1 NZ_CP098247:318010-318285 [Oxalobacter aliiformigenes]
MELKWTSKAASDLSRLYEFLAPANKKAAARAIQALIKAPNILLTNPRISEQLFEFESQEVRRILIGNYEIRYEIKSSTIF
VLRVWHTRENR

Download         Length: 276 bp

Antitoxin


Download         Length: 93 a.a.        Molecular weight: 10294.71 Da        Isoelectric Point: 4.5084

>AT247351 WP_269277898.1 NZ_CP098247:317732-318010 [Oxalobacter aliiformigenes]
MKQTQSKVFTAHVPLPLADKVDQLAARIERSRGWVIKQALSAWIEQEEERYQMTLEALADVDAGRVVDHEAMLAWAESLG
TDDPLPLPEPGK

Download         Length: 279 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References