247125

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) yfjZ-ypjF/CbtA-CbeA
Location 1312726..1313384 Replicon chromosome
Accession NZ_CP098214
Organism Escherichia coli strain Z0117EC0036

Toxin (Protein)


Gene name ypjF Uniprot ID -
Locus tag NBY15_RS06545 Protein ID WP_021520983.1
Coordinates 1312726..1313046 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag NBY15_RS06550 Protein ID WP_021520982.1
Coordinates 1313067..1313384 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY15_RS06530 (1308148) 1308148..1309596 - 1449 WP_220401795.1 NADP-dependent succinate-semialdehyde dehydrogenase -
NBY15_RS06535 (1309619) 1309619..1310887 - 1269 WP_000271981.1 L-2-hydroxyglutarate oxidase -
NBY15_RS06540 (1310907) 1310907..1311884 - 978 WP_220401794.1 glutarate dioxygenase GlaH -
NBY15_RS06545 (1312726) 1312726..1313046 - 321 WP_021520983.1 TA system toxin CbtA family protein Toxin
NBY15_RS06550 (1313067) 1313067..1313384 - 318 WP_021520982.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
NBY15_RS06555 (1313403) 1313403..1313624 - 222 WP_021520981.1 DUF987 domain-containing protein -
NBY15_RS06560 (1313633) 1313633..1314109 - 477 WP_021520980.1 RadC family protein -
NBY15_RS06565 (1314125) 1314125..1314583 - 459 WP_021520979.1 antirestriction protein -
NBY15_RS06570 (1314679) 1314679..1314918 - 240 WP_021520978.1 DUF905 domain-containing protein -
NBY15_RS06575 (1315018) 1315018..1315926 - 909 WP_021520977.1 Ivy family c-type lysozyme inhibitor -
NBY15_RS06580 (1315995) 1315995..1316162 - 168 Protein_1294 DUF4339 domain-containing protein -
NBY15_RS06585 (1316200) 1316200..1316895 - 696 WP_021520976.1 hypothetical protein -
NBY15_RS06590 (1317122) 1317122..1317949 - 828 WP_021520975.1 DUF932 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-104)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12162.18 Da        Isoelectric Point: 7.1656

>T247125 WP_021520983.1 NZ_CP098214:c1313046-1312726 [Escherichia coli]
MKTLPATTLWAAKPCLSPVIVWQMLLSRLLDQHYGLTLNDTPFSDETVIKEHIDAGISLADAVNFLVEKYELVRIDRKGF
SWQEQSPFITAVDILKARRAMREMRT

Download         Length: 321 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11997.54 Da        Isoelectric Point: 6.3142

>AT247125 WP_021520982.1 NZ_CP098214:c1313384-1313067 [Escherichia coli]
MSNITWGLQRDITPRLGARLVQEGNQLHYLADRASITGKFSDVECRKLDETFPHFISQMESMLTTDELNPRHAHCVTLYH
NGFTCEADTLGSCGYIYITVYPTQR

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References