Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 4233639..4234166 | Replicon | chromosome |
Accession | NZ_CP098211 | ||
Organism | Escherichia coli strain Z0117EC0040 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A7H9NEL1 |
Locus tag | NBY16_RS20400 | Protein ID | WP_023220446.1 |
Coordinates | 4233639..4233914 (-) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A7H9NIT7 |
Locus tag | NBY16_RS20405 | Protein ID | WP_023220445.1 |
Coordinates | 4233918..4234166 (-) | Length | 83 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
NBY16_RS20390 (4229255) | 4229255..4232371 | + | 3117 | WP_048963609.1 | HsdR family type I site-specific deoxyribonuclease | - |
NBY16_RS20395 (4232727) | 4232727..4233509 | - | 783 | WP_244470603.1 | helix-turn-helix transcriptional regulator | - |
NBY16_RS20400 (4233639) | 4233639..4233914 | - | 276 | WP_023220446.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
NBY16_RS20405 (4233918) | 4233918..4234166 | - | 249 | WP_023220445.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
NBY16_RS20410 (4234242) | 4234242..4235084 | - | 843 | WP_048963608.1 | DUF4942 domain-containing protein | - |
NBY16_RS20415 (4235197) | 4235197..4235547 | - | 351 | WP_053087800.1 | DUF5983 family protein | - |
NBY16_RS20420 (4235574) | 4235574..4235750 | - | 177 | Protein_4008 | DUF5983 family protein | - |
NBY16_RS20425 (4235741) | 4235741..4236115 | - | 375 | WP_023220442.1 | TA system toxin CbtA family protein | - |
NBY16_RS20430 (4236161) | 4236161..4236808 | - | 648 | WP_048963607.1 | hypothetical protein | - |
NBY16_RS20435 (4236805) | 4236805..4237176 | - | 372 | WP_048963606.1 | type IV toxin-antitoxin system YeeU family antitoxin | - |
NBY16_RS20440 (4237148) | 4237148..4237516 | - | 369 | WP_023220439.1 | type IV toxin-antitoxin system YeeU family antitoxin | - |
NBY16_RS20445 (4237534) | 4237534..4237755 | - | 222 | WP_048963605.1 | DUF987 family protein | - |
NBY16_RS20450 (4237752) | 4237752..4238042 | - | 291 | WP_048963604.1 | hypothetical protein | - |
NBY16_RS20455 (4238058) | 4238058..4238537 | - | 480 | WP_048963603.1 | DNA repair protein RadC | - |
NBY16_RS20460 (4238548) | 4238548..4239024 | - | 477 | WP_048963602.1 | antirestriction protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Genomic island | - | fimB | 4217609..4257518 | 39909 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7H9NEL1 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7H9NIT7 |