Detailed information of TA system TA024706

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yxiD-yxxD/-
• Location: 1954317..1955098
• Replicon: chromosome
• Accession: NC_014019
• Organism: Bacillus megaterium QM B1551

Toxin (Protein)

• Gene name: yxiD
• Uniprot ID: -
• Locus tag: BMQ_RS28745
• Protein ID: WP_075420344.1
• Coordinates: 1954317..1954667 (+)
• Length: 117 a.a.

Antitoxin (Protein)

• Gene name: yxxD
• Uniprot ID: D5DPQ5
• Locus tag: BMQ_RS09520
• Protein ID: WP_013056651.1
• Coordinates: 1954670..1955098 (+)
• Length: 143 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
BMQ_RS09500	1949819..1950082	-	264	WP_013056647.1	helix-turn-helix transcriptional regulator	-
BMQ_RS09505	1950654..1951502	+	849	WP_162485295.1	GIY-YIG nuclease family protein	-
BMQ_RS09510	1951619..1953775	+	2157	WP_013056649.1	type IA DNA topoisomerase	-
BMQ_RS28745	1954317..1954667	+	351	WP_075420344.1	HNH endonuclease	Toxin
BMQ_RS09520	1954670..1955098	+	429	WP_013056651.1	SMI1/KNR4 family protein	Antitoxin
BMQ_RS09525	1955616..1956767	+	1152	WP_013056652.1	suppressor of fused domain protein	-
BMQ_RS09530	1957245..1959110	+	1866	WP_013056653.1	AAA family ATPase	-
BMQ_RS27730	1959103..1960020	+	918	WP_049787036.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 117 a.a.
• Molecular weight: 13874.50 Da
• Isoelectric Point: 9.3682

>T24706 WP_075420344.1 NC_014019:1954317-1954667 [Bacillus megaterium QM B1551]
VEFLKESLRNNKFEKLTPKETAKHRGRFTTSLKNKLIEEWEEKTNQKWPRYTEEVYDQSGEIARHIGQPYDAHHLIENNF
SGPHEWWNIHPAKYPDEHQQGIHGKGAPSRMLFPRR

Nucleotide

• Length: 351 bp

>T24706 NC_014019:1954317-1954667 [Bacillus megaterium QM B1551]
GTGGAATTTCTAAAAGAATCCTTAAGAAATAATAAATTTGAAAAATTAACACCTAAAGAAACAGCTAAGCATAGAGGTAG
ATTTACTACAAGCCTAAAAAACAAGTTAATTGAAGAATGGGAAGAAAAAACCAATCAAAAGTGGCCACGATATACAGAGG
AAGTATATGATCAAAGTGGAGAAATTGCTAGACATATTGGTCAACCATACGATGCTCATCATCTTATAGAAAACAATTTT
TCTGGTCCTCATGAATGGTGGAATATTCATCCTGCTAAATACCCTGACGAGCATCAGCAGGGGATTCATGGAAAAGGAGC
ACCATCAAGAATGTTATTCCCTAGGAGGTAA

Antitoxin

Protein

• Length: 143 a.a.
• Molecular weight: 16623.64 Da
• Isoelectric Point: 3.9139

>AT24706 WP_013056651.1 NC_014019:1954670-1955098 [Bacillus megaterium QM B1551]
MADFKFINNGENKIYNLSEEEILKAEDRMGIRFPDDLRQLYLEVGYGFIKEPSNNAINRIMGPGTVANVKLREGVFEFDP
DLDELDEEDKLIFFEVNEGIYISLDLKLPNNPVFYFDTQIADSLEDFLKKFINDNEYYIDLE

Nucleotide

• Length: 429 bp

>AT24706 NC_014019:1954670-1955098 [Bacillus megaterium QM B1551]
ATGGCGGATTTTAAGTTTATTAATAATGGAGAAAATAAAATTTATAATTTATCTGAAGAGGAGATTTTAAAAGCGGAAGA
CAGAATGGGTATCCGTTTTCCCGATGATTTAAGACAGTTATATTTAGAAGTTGGATATGGGTTCATTAAAGAGCCAAGTA
ATAATGCAATCAATAGAATTATGGGACCAGGAACGGTAGCAAATGTCAAATTACGAGAAGGAGTTTTTGAATTCGATCCA
GATTTAGACGAACTGGATGAAGAAGATAAACTTATTTTCTTTGAAGTGAATGAGGGGATATATATATCGTTAGATTTAAA
ATTGCCCAATAATCCAGTTTTTTATTTTGACACTCAGATAGCAGACTCATTAGAGGATTTTTTAAAGAAATTTATTAATG
ATAATGAGTATTACATTGATTTAGAATAA

Structures

Antitoxin

• AlphaFold DB: A0A7W3N954