Detailed information of TA system TA024703

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 2540572..2541485
• Replicon: chromosome
• Accession: NC_014012
• Organism: Shewanella violacea DSS12

Toxin (Protein)

• Gene name: -
• Uniprot ID: D4ZKI4
• Locus tag: SVI_RS10380
• Protein ID: WP_013051488.1
• Coordinates: 2541021..2541485 (+)
• Length: 155 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: SVI_RS10375
• Protein ID: WP_041419865.1
• Coordinates: 2540572..2541024 (+)
• Length: 151 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SVI_RS10360	2536923..2537213	+	291	WP_013051484.1	hypothetical protein	-
SVI_RS10365	2537279..2539546	+	2268	WP_041419864.1	TonB-dependent receptor	-
SVI_RS10370	2539692..2540363	-	672	WP_013051486.1	protein disulfide-isomerase	-
SVI_RS10375	2540572..2541024	+	453	WP_041419865.1	DUF2384 domain-containing protein	Antitoxin
SVI_RS10380	2541021..2541485	+	465	WP_013051488.1	RES family NAD+ phosphorylase	Toxin
SVI_RS10385	2541841..2543283	-	1443	WP_013051489.1	aspartate ammonia-lyase	-
SVI_RS10390	2543521..2543775	-	255	WP_157608686.1	hypothetical protein	-
SVI_RS10395	2543917..2544819	-	903	WP_197532044.1	dihydrodipicolinate synthase family protein	-
SVI_RS10400	2544816..2545262	-	447	WP_013051492.1	cupin domain-containing protein	-
SVI_RS10405	2545384..2546271	+	888	WP_013051493.1	LysR family transcriptional regulator	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (4-139)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (32-91)

Sequences

Toxin

Protein

• Length: 155 a.a.
• Molecular weight: 17448.80 Da
• Isoelectric Point: 4.5641

>T24703 WP_013051488.1 NC_014012:2541021-2541485 [Shewanella violacea DSS12]
MITAYRIVKKKWASNAFDGEGARLFGGRWNSRGQSCVYLAGSESLAILEILVHLDNAQQINHYTLFAVELDEKDIMLLDK
DALPHNWQEDPAPADTADVGDEWLNSQVSLALCVPSSIVTRERNFLLNVEHPAFDNMMNTKLELEFSMDRRLLP

Nucleotide

• Length: 465 bp

>T24703 NC_014012:2541021-2541485 [Shewanella violacea DSS12]
ATGATCACCGCCTATCGCATAGTGAAGAAAAAATGGGCCAGCAATGCCTTCGATGGTGAAGGCGCCAGGCTCTTCGGTGG
GCGCTGGAATAGTCGCGGCCAGTCCTGTGTTTATCTGGCAGGCTCCGAGTCTTTAGCTATTTTAGAGATATTGGTTCATT
TAGATAATGCCCAGCAAATCAATCATTACACCTTATTTGCTGTAGAGTTGGATGAAAAAGATATCATGTTACTGGACAAG
GATGCCCTGCCCCATAATTGGCAAGAAGACCCAGCGCCTGCAGATACGGCCGATGTGGGAGATGAATGGTTAAACAGTCA
AGTCAGTTTGGCTCTGTGTGTCCCCTCTAGCATAGTGACTCGGGAACGTAACTTTTTGCTCAATGTCGAGCATCCCGCTT
TCGATAACATGATGAATACTAAGCTAGAGCTCGAGTTTTCCATGGATAGACGACTGCTGCCATAA

Antitoxin

Protein

• Length: 151 a.a.
• Molecular weight: 16319.49 Da
• Isoelectric Point: 8.4576

>AT24703 WP_041419865.1 NC_014012:2540572-2541024 [Shewanella violacea DSS12]
MAITNVFTPASASNKVIGFWQSVGVPARGASLYEALHTGLPFEVYSNLAKVSGIEKSELASATVIASATLQRRAKAGKFN
RDESDRLYRFAEVYKSALDLFEGEGDDATRWLRNPVRGLGNKRPIDMLSTSAETEAVLNLIGRLEHGVFA

Nucleotide

• Length: 453 bp

>AT24703 NC_014012:2540572-2541024 [Shewanella violacea DSS12]
ATGGCAATTACCAATGTGTTTACGCCGGCGAGTGCAAGCAATAAAGTCATCGGCTTCTGGCAATCTGTTGGCGTTCCAGC
TCGCGGTGCCAGCTTATATGAGGCGCTGCATACTGGGCTGCCGTTCGAGGTCTATAGCAATCTAGCTAAAGTTTCCGGCA
TAGAAAAGTCTGAGCTTGCCAGTGCCACGGTTATCGCCAGTGCGACCTTACAACGCCGTGCCAAGGCGGGAAAATTCAAT
CGTGACGAGAGTGACAGGCTGTATCGTTTCGCCGAAGTGTATAAGTCAGCGCTGGATCTGTTTGAGGGTGAAGGTGATGA
TGCGACTCGCTGGCTGAGAAACCCAGTACGTGGTCTGGGTAACAAGCGTCCTATCGATATGCTGTCGACTTCGGCAGAAA
CTGAGGCGGTGCTGAATCTAATAGGCCGCTTAGAGCACGGTGTATTTGCATGA

Structures

Toxin

• AlphaFold DB: D4ZKI4