Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /BrnT(toxin)
Location 3672910..3673405 Replicon chromosome
Accession NC_014008
Organism Coraliomargarita akajimensis DSM 45221

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag CAKA_RS15190 Protein ID WP_013044787.1
Coordinates 3672910..3673173 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag CAKA_RS15195 Protein ID WP_041746385.1
Coordinates 3673163..3673405 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CAKA_RS15165 3668726..3669148 + 423 WP_148216419.1 hypothetical protein -
CAKA_RS15170 3669138..3670451 - 1314 WP_013044782.1 LssY C-terminal domain-containing protein -
CAKA_RS15175 3670844..3672073 + 1230 WP_013044784.1 TIGR03862 family flavoprotein -
CAKA_RS15180 3672139..3672549 - 411 WP_013044785.1 group III truncated hemoglobin -
CAKA_RS15185 3672565..3672771 - 207 WP_013044786.1 hypothetical protein -
CAKA_RS15190 3672910..3673173 + 264 WP_013044787.1 BrnT family toxin Toxin
CAKA_RS15195 3673163..3673405 + 243 WP_041746385.1 CopG family transcriptional regulator Antitoxin
CAKA_RS15200 3673474..3675024 + 1551 WP_013044789.1 DUF4955 domain-containing protein -
CAKA_RS15205 3675349..3675810 + 462 WP_052293185.1 division/cell wall cluster transcriptional repressor MraZ -
CAKA_RS15210 3676047..3677003 + 957 WP_013044791.1 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH -
CAKA_RS15215 3677028..3677408 + 381 WP_013044792.1 hypothetical protein -
CAKA_RS15220 3677435..3677644 + 210 WP_013044793.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(5-80)

Antitoxin

CopG antitoxin

(5-68)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10278.69 Da        Isoelectric Point: 7.7480

>T24701 WP_013044787.1 NC_014008:3672910-3673173 [Coraliomargarita akajimensis DSM 45221]
MDCEFDPQKSAINKEKHGIDFIEAQQLWQDITALEVPARSETEERYALIAFYNCKIWTVIFTRREGKIRIISCRRARDGE
KKAYHNS

Download         Length: 264 bp

>T24701 NC_014008:3672910-3673173 [Coraliomargarita akajimensis DSM 45221]
ATGGATTGTGAGTTCGATCCTCAAAAATCTGCAATAAACAAGGAGAAGCACGGCATTGATTTCATCGAAGCTCAGCAGCT
TTGGCAGGACATCACGGCTTTAGAAGTCCCTGCTAGAAGTGAAACAGAAGAGAGATATGCCTTGATTGCTTTCTATAATT
GCAAGATTTGGACTGTGATCTTCACCAGGAGAGAAGGGAAAATTAGAATCATATCATGTCGGAGAGCGAGAGATGGCGAA
AAAAAAGCATACCATAACAGCTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9500.73 Da        Isoelectric Point: 4.5837

>AT24701 WP_041746385.1 NC_014008:3673163-3673405 [Coraliomargarita akajimensis DSM 45221]
ITAEELDRRFDEGEDITEFLDFDKASRPNLEQRRVNLDLPTWMIETLDSEAKRIGVTRQSIMKVWISERIKLEQAERLHA

Download         Length: 243 bp

>AT24701 NC_014008:3673163-3673405 [Coraliomargarita akajimensis DSM 45221]
ATAACAGCTGAAGAACTCGATCGCCGCTTTGATGAAGGCGAAGACATCACAGAGTTCTTGGATTTCGATAAGGCCTCTAG
ACCAAATCTGGAGCAAAGACGCGTGAACCTAGATCTCCCAACTTGGATGATTGAGACTCTCGATAGTGAAGCAAAGCGGA
TTGGAGTAACACGTCAGTCTATCATGAAGGTTTGGATTTCTGAGAGAATCAAACTCGAGCAAGCGGAACGACTTCATGCG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References