Detailed information of TA system TA024701

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 3672910..3673405
• Replicon: chromosome
• Accession: NC_014008
• Organism: Coraliomargarita akajimensis DSM 45221

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CAKA_RS15190
• Protein ID: WP_013044787.1
• Coordinates: 3672910..3673173 (+)
• Length: 88 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CAKA_RS15195
• Protein ID: WP_041746385.1
• Coordinates: 3673163..3673405 (+)
• Length: 81 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CAKA_RS15165	3668726..3669148	+	423	WP_148216419.1	hypothetical protein	-
CAKA_RS15170	3669138..3670451	-	1314	WP_013044782.1	LssY C-terminal domain-containing protein	-
CAKA_RS15175	3670844..3672073	+	1230	WP_013044784.1	TIGR03862 family flavoprotein	-
CAKA_RS15180	3672139..3672549	-	411	WP_013044785.1	group III truncated hemoglobin	-
CAKA_RS15185	3672565..3672771	-	207	WP_013044786.1	hypothetical protein	-
CAKA_RS15190	3672910..3673173	+	264	WP_013044787.1	BrnT family toxin	Toxin
CAKA_RS15195	3673163..3673405	+	243	WP_041746385.1	CopG family transcriptional regulator	Antitoxin
CAKA_RS15200	3673474..3675024	+	1551	WP_013044789.1	DUF4955 domain-containing protein	-
CAKA_RS15205	3675349..3675810	+	462	WP_052293185.1	division/cell wall cluster transcriptional repressor MraZ	-
CAKA_RS15210	3676047..3677003	+	957	WP_013044791.1	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	-
CAKA_RS15215	3677028..3677408	+	381	WP_013044792.1	hypothetical protein	-
CAKA_RS15220	3677435..3677644	+	210	WP_013044793.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (5-80)

Antitoxin

• CopG antitoxin (5-68)

Sequences

Toxin

Protein

• Length: 88 a.a.
• Molecular weight: 10278.69 Da
• Isoelectric Point: 7.7480

>T24701 WP_013044787.1 NC_014008:3672910-3673173 [Coraliomargarita akajimensis DSM 45221]
MDCEFDPQKSAINKEKHGIDFIEAQQLWQDITALEVPARSETEERYALIAFYNCKIWTVIFTRREGKIRIISCRRARDGE
KKAYHNS

Nucleotide

• Length: 264 bp

>T24701 NC_014008:3672910-3673173 [Coraliomargarita akajimensis DSM 45221]
ATGGATTGTGAGTTCGATCCTCAAAAATCTGCAATAAACAAGGAGAAGCACGGCATTGATTTCATCGAAGCTCAGCAGCT
TTGGCAGGACATCACGGCTTTAGAAGTCCCTGCTAGAAGTGAAACAGAAGAGAGATATGCCTTGATTGCTTTCTATAATT
GCAAGATTTGGACTGTGATCTTCACCAGGAGAGAAGGGAAAATTAGAATCATATCATGTCGGAGAGCGAGAGATGGCGAA
AAAAAAGCATACCATAACAGCTGA

Antitoxin

Protein

• Length: 81 a.a.
• Molecular weight: 9500.73 Da
• Isoelectric Point: 4.5837

>AT24701 WP_041746385.1 NC_014008:3673163-3673405 [Coraliomargarita akajimensis DSM 45221]
ITAEELDRRFDEGEDITEFLDFDKASRPNLEQRRVNLDLPTWMIETLDSEAKRIGVTRQSIMKVWISERIKLEQAERLHA

Nucleotide

• Length: 243 bp

>AT24701 NC_014008:3673163-3673405 [Coraliomargarita akajimensis DSM 45221]
ATAACAGCTGAAGAACTCGATCGCCGCTTTGATGAAGGCGAAGACATCACAGAGTTCTTGGATTTCGATAAGGCCTCTAG
ACCAAATCTGGAGCAAAGACGCGTGAACCTAGATCTCCCAACTTGGATGATTGAGACTCTCGATAGTGAAGCAAAGCGGA
TTGGAGTAACACGTCAGTCTATCATGAAGGTTTGGATTTCTGAGAGAATCAAACTCGAGCAAGCGGAACGACTTCATGCG
TAG