Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2239691..2239962 Replicon chromosome
Accession NZ_CP098197
Organism Escherichia coli strain Z0117EC0062

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2239821..2239924 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2239691..2239962 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY21_RS10740 2236246..2236908 - 663 WP_000944256.1 exodeoxyribonuclease X -
NBY21_RS10745 2236932..2237588 - 657 WP_076797519.1 carbon-nitrogen hydrolase family protein YobB -
NBY21_RS10750 2237690..2237920 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NBY21_RS10755 2238059..2238433 + 375 WP_000168747.1 CopC domain-containing protein YobA -
NBY21_RS10760 2238437..2239309 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
NBY21_RS10765 2239322..2239663 + 342 WP_000976472.1 YebY family protein -
- 2239691..2239962 - 272 - - Antitoxin
- 2239821..2239924 + 104 - - Toxin
NBY21_RS10770 2240059..2240715 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
NBY21_RS10775 2240716..2240907 - 192 WP_001296140.1 YebW family protein -
NBY21_RS10780 2241012..2241248 - 237 WP_001295499.1 YebV family protein -
NBY21_RS10785 2241366..2242805 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2232381..2255802 23421


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246970 NZ_CP098197:2239821-2239924 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT246970 NZ_CP098197:c2239962-2239691 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References