Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2189556..2189827 Replicon chromosome
Accession NZ_CP098192
Organism Escherichia coli strain Z0117EC0116

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2189686..2189789 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2189556..2189827 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY24_RS10505 2186111..2186773 - 663 WP_000944256.1 exodeoxyribonuclease X -
NBY24_RS10510 2186797..2187453 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein YobB -
NBY24_RS10515 2187555..2187785 - 231 WP_000916763.1 DNA polymerase III subunit theta -
NBY24_RS10520 2187924..2188298 + 375 WP_000204699.1 CopC domain-containing protein YobA -
NBY24_RS10525 2188302..2189174 + 873 WP_000879334.1 copper homeostasis membrane protein CopD -
NBY24_RS10530 2189187..2189528 + 342 WP_000976492.1 YebY family protein -
- 2189556..2189827 - 272 - - Antitoxin
- 2189686..2189789 + 104 - - Toxin
NBY24_RS10535 2189924..2190580 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
NBY24_RS10540 2190581..2190772 - 192 WP_001296140.1 YebW family protein -
NBY24_RS10545 2190877..2191113 - 237 WP_001295499.1 YebV family protein -
NBY24_RS10550 2191231..2192670 - 1440 WP_000057024.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T246916 NZ_CP098192:2189686-2189789 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT246916 NZ_CP098192:c2189827-2189556 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References