24690

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3048036..3048702 Replicon chromosome
Accession NC_013971
Organism Erwinia amylovora ATCC 49946

Toxin (Protein)


Gene name cptA Uniprot ID A0A830ZTB8
Locus tag EAM_RS13655 Protein ID WP_004161808.1
Coordinates 3048036..3048455 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D4HWC2
Locus tag EAM_RS13660 Protein ID WP_004155593.1
Coordinates 3048436..3048702 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
EAM_RS13640 (EAM_2780) 3044028..3045707 + 1680 WP_004155599.1 type III effector -
EAM_RS13645 (EAM_2781) 3046217..3047170 + 954 WP_004155597.1 DMT family transporter -
EAM_RS13650 (EAM_2782) 3047400..3047918 + 519 WP_004155596.1 flavodoxin FldB -
EAM_RS13655 (EAM_2783) 3048036..3048455 - 420 WP_004161808.1 protein YgfX Toxin
EAM_RS13660 (EAM_2784) 3048436..3048702 - 267 WP_004155593.1 FAD assembly factor SdhE Antitoxin
EAM_RS13665 (EAM_2785) 3048928..3049914 + 987 WP_004155590.1 tRNA-modifying protein YgfZ -
EAM_RS13670 (EAM_2786) 3049915..3050574 - 660 WP_004155588.1 hemolysin III family protein -
EAM_RS13675 (EAM_2787) 3050787..3051395 + 609 WP_004155587.1 HD domain-containing protein -
EAM_RS13680 (EAM_2788) 3051500..3052229 - 730 Protein_2661 SDR family oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-131)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16366.46 Da        Isoelectric Point: 11.9444

>T24690 WP_004161808.1 NC_013971:c3048455-3048036 [Erwinia amylovora ATCC 49946]
VVLWQCELRPSRLAQRFSLLLHGAVMLALLLPTWPASSGLVRMLLLVLVLLECIRSRRRIGRRQGDIALLEGHELRWRQR
EWCIISRPWLTGQAILLLLQDTHGQRERLWLFADGMEKRNWRQLRLQLLNSKVQGNGWC

Download         Length: 420 bp

>T24690 NC_013971:c3048455-3048036 [Erwinia amylovora ATCC 49946]
GTGGTCCTGTGGCAATGTGAACTGCGGCCATCAAGGCTGGCACAGCGGTTTTCGCTGCTGCTGCATGGGGCAGTGATGCT
GGCGCTGCTATTGCCGACATGGCCCGCCAGCTCTGGCCTGGTGCGGATGCTGTTGCTGGTTTTGGTACTGTTGGAGTGCA
TACGCAGTCGGCGGCGCATTGGTCGTCGCCAGGGGGATATCGCTCTGTTGGAAGGGCATGAGCTACGCTGGCGTCAACGC
GAGTGGTGCATTATTTCCCGTCCGTGGCTGACCGGGCAGGCAATCCTGCTGTTACTACAGGATACTCATGGACAGCGCGA
GCGACTATGGCTGTTCGCCGACGGCATGGAAAAACGTAACTGGCGTCAGCTGCGCCTGCAATTGCTGAACAGTAAAGTAC
AGGGGAATGGCTGGTGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10498.07 Da        Isoelectric Point: 6.4605

>AT24690 WP_004155593.1 NC_013971:c3048702-3048436 [Erwinia amylovora ATCC 49946]
MDITNKSRIHWACRRGMRELDISIMPFFQYEFDSLNDSDKRLFVRLLESDDPDLFNWLMNHGEPADVELKRMVALIQQRN
KQRGPVAM

Download         Length: 267 bp

>AT24690 NC_013971:c3048702-3048436 [Erwinia amylovora ATCC 49946]
ATGGATATTACAAATAAATCACGTATTCACTGGGCATGCCGTCGCGGCATGCGCGAGCTGGATATCTCGATCATGCCCTT
TTTCCAGTATGAATTTGACTCGCTGAACGACAGCGATAAACGGCTGTTCGTTCGCCTGCTGGAGAGCGATGACCCGGACC
TGTTCAACTGGCTGATGAACCACGGCGAGCCGGCAGACGTGGAGCTGAAAAGGATGGTGGCGCTAATCCAACAAAGAAAT
AAACAACGTGGTCCTGTGGCAATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A830ZTB8

Antitoxin

Source ID Structure
AlphaFold DB A0A831A3F0

References