Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | relBE/ParE-RelB |
| Location | 904312..904765 | Replicon | chromosome |
| Accession | NC_013971 | ||
| Organism | Erwinia amylovora ATCC 49946 | ||
Toxin (Protein)
| Gene name | relE | Uniprot ID | - |
| Locus tag | EAM_RS03910 | Protein ID | WP_013035888.1 |
| Coordinates | 904529..904765 (+) | Length | 79 a.a. |
Antitoxin (Protein)
| Gene name | relB | Uniprot ID | D4HZA2 |
| Locus tag | EAM_RS03905 | Protein ID | WP_004159527.1 |
| Coordinates | 904312..904539 (+) | Length | 76 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EAM_RS03895 (EAM_0800) | 903236..903640 | + | 405 | WP_013035886.1 | hypothetical protein | - |
| EAM_RS03900 (EAM_0801) | 903704..903991 | - | 288 | WP_004159528.1 | SymE family type I addiction module toxin | - |
| EAM_RS03905 (EAM_0802) | 904312..904539 | + | 228 | WP_004159527.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| EAM_RS03910 (EAM_0803) | 904529..904765 | + | 237 | WP_013035888.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| EAM_RS03915 | 904752..904970 | - | 219 | WP_004159522.1 | hypothetical protein | - |
| EAM_RS03920 (EAM_0805) | 905298..907514 | + | 2217 | Protein_756 | ferrichrome porin FhuA | - |
| EAM_RS03925 (EAM_0806) | 907563..908357 | + | 795 | WP_004159512.1 | Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC | - |
| EAM_RS03930 (EAM_0807) | 908372..909250 | + | 879 | WP_004159509.1 | Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 79 a.a. Molecular weight: 9135.79 Da Isoelectric Point: 9.0876
>T24686 WP_013035888.1 NC_013971:904529-904765 [Erwinia amylovora ATCC 49946]
ISYELLFDPWALKEWKKLGATVREQFKKKLAEVLVNLQVESARLRDHPDCCKIKLKSSGYRLVYQVQDEQLVMLVISV
ISYELLFDPWALKEWKKLGATVREQFKKKLAEVLVNLQVESARLRDHPDCCKIKLKSSGYRLVYQVQDEQLVMLVISV
Download Length: 237 bp
>T24686 NC_013971:904529-904765 [Erwinia amylovora ATCC 49946]
ATAAGCTATGAACTGCTCTTCGATCCCTGGGCCTTAAAAGAGTGGAAAAAACTGGGCGCAACGGTTCGGGAACAGTTCAA
AAAGAAACTGGCGGAAGTGCTGGTAAACCTGCAGGTGGAATCAGCCAGGCTGAGAGATCACCCGGACTGCTGCAAAATAA
AGCTGAAATCATCGGGTTATCGTCTGGTATATCAGGTTCAGGATGAACAGCTGGTAATGTTGGTTATAAGCGTTTGA
ATAAGCTATGAACTGCTCTTCGATCCCTGGGCCTTAAAAGAGTGGAAAAAACTGGGCGCAACGGTTCGGGAACAGTTCAA
AAAGAAACTGGCGGAAGTGCTGGTAAACCTGCAGGTGGAATCAGCCAGGCTGAGAGATCACCCGGACTGCTGCAAAATAA
AGCTGAAATCATCGGGTTATCGTCTGGTATATCAGGTTCAGGATGAACAGCTGGTAATGTTGGTTATAAGCGTTTGA
Antitoxin
Download Length: 76 a.a. Molecular weight: 8435.90 Da Isoelectric Point: 7.9766
>AT24686 WP_004159527.1 NC_013971:904312-904539 [Erwinia amylovora ATCC 49946]
VRLDDKLKSKACAVLDELDVSPTEAVRLLFQYIAENERLPLKALTVSDEKDALLKTVRERLASLQKGIKVTLDKL
VRLDDKLKSKACAVLDELDVSPTEAVRLLFQYIAENERLPLKALTVSDEKDALLKTVRERLASLQKGIKVTLDKL
Download Length: 228 bp
>AT24686 NC_013971:904312-904539 [Erwinia amylovora ATCC 49946]
GTGCGGCTGGATGACAAACTGAAAAGCAAAGCCTGTGCAGTTCTGGATGAACTGGATGTATCGCCAACGGAGGCGGTCCG
GCTGTTGTTCCAGTATATAGCGGAAAATGAGCGCCTACCGCTGAAAGCGCTGACGGTAAGTGATGAAAAAGACGCGCTGC
TGAAAACGGTTCGCGAAAGGCTGGCATCGCTACAGAAGGGAATAAAGGTAACGCTGGATAAGCTATGA
GTGCGGCTGGATGACAAACTGAAAAGCAAAGCCTGTGCAGTTCTGGATGAACTGGATGTATCGCCAACGGAGGCGGTCCG
GCTGTTGTTCCAGTATATAGCGGAAAATGAGCGCCTACCGCTGAAAGCGCTGACGGTAAGTGATGAAAAAGACGCGCTGC
TGAAAACGGTTCGCGAAAGGCTGGCATCGCTACAGAAGGGAATAAAGGTAACGCTGGATAAGCTATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|