Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2012988..2013133 | Replicon | chromosome |
| Accession | NZ_CP098167 | ||
| Organism | Klebsiella pneumoniae strain Z0117KP0004 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2013024..2013126 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2012988..2013133 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NBY32_RS09655 | 2008118..2010178 | + | 2061 | WP_004148850.1 | oligopeptidase B | - |
| NBY32_RS09660 | 2010182..2010841 | - | 660 | WP_032435029.1 | exodeoxyribonuclease X | - |
| NBY32_RS09665 | 2010920..2011150 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| NBY32_RS09670 | 2011263..2011637 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| NBY32_RS09675 | 2011641..2012510 | + | 870 | WP_032435031.1 | copper homeostasis membrane protein CopD | - |
| NBY32_RS09680 | 2012527..2012865 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2012988..2013133 | - | 146 | - | - | Antitoxin |
| - | 2013024..2013126 | + | 103 | - | - | Toxin |
| NBY32_RS09685 | 2013501..2013644 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| NBY32_RS09690 | 2013749..2014717 | - | 969 | WP_004151446.1 | VirK/YbjX family protein | - |
| NBY32_RS09695 | 2014874..2015527 | + | 654 | WP_004891053.1 | protein-serine/threonine phosphatase | - |
| NBY32_RS09700 | 2015524..2015715 | - | 192 | WP_002911395.1 | YebW family protein | - |
| NBY32_RS09705 | 2015813..2016052 | - | 240 | WP_002911393.1 | YebV family protein | - |
| NBY32_RS09710 | 2016168..2017601 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T246776 NZ_CP098167:2013024-2013126 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT246776 NZ_CP098167:c2013133-2012988 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT