Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3342977..3343122 Replicon chromosome
Accession NZ_CP098165
Organism Klebsiella pneumoniae strain Z0117KP0005

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3342984..3343086 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3342977..3343122 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY34_RS16115 3338509..3339942 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NBY34_RS16120 3340058..3340297 + 240 WP_002911393.1 YebV family protein -
NBY34_RS16125 3340395..3340586 + 192 WP_002911395.1 YebW family protein -
NBY34_RS16130 3340583..3341236 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
NBY34_RS16135 3341393..3342361 + 969 WP_004151446.1 VirK/YbjX family protein -
NBY34_RS16140 3342466..3342609 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3342977..3343122 + 146 - - Antitoxin
- 3342984..3343086 - 103 - - Toxin
NBY34_RS16145 3343245..3343583 - 339 WP_002911404.1 YebY family protein -
NBY34_RS16150 3343600..3344469 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
NBY34_RS16155 3344473..3344847 - 375 WP_004151448.1 CopC domain-containing protein YobA -
NBY34_RS16160 3344960..3345190 + 231 WP_002911406.1 DNA polymerase III subunit theta -
NBY34_RS16165 3345269..3345928 + 660 WP_032435029.1 exodeoxyribonuclease X -
NBY34_RS16170 3345932..3347992 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246765 NZ_CP098165:c3343086-3342984 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246765 NZ_CP098165:3342977-3343122 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References