Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1960436..1960581 Replicon chromosome
Accession NZ_CP098149
Organism Klebsiella pneumoniae strain Z0117KP0019

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1960472..1960574 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1960436..1960581 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY46_RS09475 1955566..1957626 + 2061 WP_004148850.1 oligopeptidase B -
NBY46_RS09480 1957630..1958289 - 660 WP_032435029.1 exodeoxyribonuclease X -
NBY46_RS09485 1958368..1958598 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NBY46_RS09490 1958711..1959085 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NBY46_RS09495 1959089..1959958 + 870 WP_032435031.1 copper homeostasis membrane protein CopD -
NBY46_RS09500 1959975..1960313 + 339 WP_002911404.1 YebY family protein -
- 1960436..1960581 - 146 - - Antitoxin
- 1960472..1960574 + 103 - - Toxin
NBY46_RS09505 1960949..1961092 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NBY46_RS09510 1961197..1962165 - 969 WP_004151446.1 VirK/YbjX family protein -
NBY46_RS09515 1962322..1962975 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
NBY46_RS09520 1962972..1963163 - 192 WP_002911395.1 YebW family protein -
NBY46_RS09525 1963261..1963500 - 240 WP_002911393.1 YebV family protein -
NBY46_RS09530 1963616..1965049 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246713 NZ_CP098149:1960472-1960574 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246713 NZ_CP098149:c1960581-1960436 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References