Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3379999..3380144 Replicon chromosome
Accession NZ_CP098145
Organism Klebsiella pneumoniae strain Z0117KP0020

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3380006..3380108 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3379999..3380144 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY48_RS16410 3375531..3376964 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
NBY48_RS16415 3377080..3377319 + 240 WP_002911393.1 YebV family protein -
NBY48_RS16420 3377417..3377608 + 192 WP_002911395.1 YebW family protein -
NBY48_RS16425 3377605..3378258 - 654 WP_004891053.1 protein-serine/threonine phosphatase -
NBY48_RS16430 3378415..3379383 + 969 WP_004151446.1 VirK/YbjX family protein -
NBY48_RS16435 3379488..3379631 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 3379999..3380144 + 146 - - Antitoxin
- 3380006..3380108 - 103 - - Toxin
NBY48_RS16440 3380267..3380605 - 339 WP_002911404.1 YebY family protein -
NBY48_RS16445 3380622..3381491 - 870 WP_032435031.1 copper homeostasis membrane protein CopD -
NBY48_RS16450 3381495..3381869 - 375 WP_004151448.1 CopC domain-containing protein YobA -
NBY48_RS16455 3381982..3382212 + 231 WP_002911406.1 DNA polymerase III subunit theta -
NBY48_RS16460 3382291..3382950 + 660 WP_032435029.1 exodeoxyribonuclease X -
NBY48_RS16465 3382954..3385014 - 2061 WP_004148850.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246700 NZ_CP098145:c3380108-3380006 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246700 NZ_CP098145:3379999-3380144 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References