Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1864038..1864183 Replicon chromosome
Accession NZ_CP098141
Organism Klebsiella pneumoniae strain Z0117KP0025

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1864074..1864176 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1864038..1864183 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY50_RS10480 1859168..1861228 + 2061 WP_004151449.1 oligopeptidase B -
NBY50_RS10485 1861232..1861891 - 660 WP_002911407.1 exodeoxyribonuclease X -
NBY50_RS10490 1861970..1862200 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NBY50_RS10495 1862313..1862687 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NBY50_RS10500 1862691..1863560 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NBY50_RS10505 1863577..1863915 + 339 WP_002911404.1 YebY family protein -
- 1864038..1864183 - 146 - - Antitoxin
- 1864074..1864176 + 103 - - Toxin
NBY50_RS10510 1864551..1864694 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NBY50_RS10515 1864799..1865767 - 969 WP_014907334.1 VirK/YbjX family protein -
NBY50_RS10520 1865924..1866577 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
NBY50_RS10525 1866574..1866765 - 192 WP_002911395.1 YebW family protein -
NBY50_RS10530 1866863..1867102 - 240 WP_002911393.1 YebV family protein -
NBY50_RS10535 1867218..1868651 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246682 NZ_CP098141:1864074-1864176 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246682 NZ_CP098141:c1864183-1864038 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References