Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 5135799..5135944 Replicon chromosome
Accession NZ_CP098136
Organism Klebsiella pneumoniae strain Z0117KP0027

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 5135835..5135937 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 5135799..5135944 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY52_RS26425 5130929..5132989 + 2061 WP_004151449.1 oligopeptidase B -
NBY52_RS26430 5132993..5133652 - 660 WP_002911407.1 exodeoxyribonuclease X -
NBY52_RS26435 5133731..5133961 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NBY52_RS26440 5134074..5134448 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NBY52_RS26445 5134452..5135321 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NBY52_RS26450 5135338..5135676 + 339 WP_002911404.1 YebY family protein -
- 5135799..5135944 - 146 - - Antitoxin
- 5135835..5135937 + 103 - - Toxin
NBY52_RS26455 5136312..5136455 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NBY52_RS26460 5136560..5137528 - 969 WP_014907334.1 VirK/YbjX family protein -
NBY52_RS26465 5137685..5138338 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
NBY52_RS26470 5138335..5138526 - 192 WP_002911395.1 YebW family protein -
NBY52_RS26475 5138624..5138863 - 240 WP_002911393.1 YebV family protein -
NBY52_RS26480 5138979..5140412 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246670 NZ_CP098136:5135835-5135937 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246670 NZ_CP098136:c5135944-5135799 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References