Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1961434..1961579 Replicon chromosome
Accession NZ_CP098123
Organism Klebsiella pneumoniae strain Z0117KP0042

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1961470..1961572 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1961434..1961579 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NBY58_RS09555 1956564..1958624 + 2061 WP_004151449.1 oligopeptidase B -
NBY58_RS09560 1958628..1959287 - 660 WP_002911407.1 exodeoxyribonuclease X -
NBY58_RS09565 1959366..1959596 - 231 WP_002911406.1 DNA polymerase III subunit theta -
NBY58_RS09570 1959709..1960083 + 375 WP_004151448.1 CopC domain-containing protein YobA -
NBY58_RS09575 1960087..1960956 + 870 WP_004189267.1 copper homeostasis membrane protein CopD -
NBY58_RS09580 1960973..1961311 + 339 WP_002911404.1 YebY family protein -
- 1961434..1961579 - 146 - - Antitoxin
- 1961470..1961572 + 103 - - Toxin
NBY58_RS09585 1961947..1962090 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
NBY58_RS09590 1962195..1963163 - 969 WP_014907334.1 VirK/YbjX family protein -
NBY58_RS09595 1963320..1963973 + 654 WP_009484457.1 protein-serine/threonine phosphatase -
NBY58_RS09600 1963970..1964161 - 192 WP_002911395.1 YebW family protein -
NBY58_RS09605 1964259..1964498 - 240 WP_002911393.1 YebV family protein -
NBY58_RS09610 1964614..1966047 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T246609 NZ_CP098123:1961470-1961572 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT246609 NZ_CP098123:c1961579-1961434 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References