Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3367889..3368427 Replicon chromosome
Accession NZ_CP098040
Organism Providencia rettgeri strain 18004577

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag L3Q80_RS15895 Protein ID WP_140172124.1
Coordinates 3368137..3368427 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L3Q80_RS15890 Protein ID WP_181489335.1
Coordinates 3367889..3368140 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q80_RS15875 (L3Q80_15865) 3364303..3365322 + 1020 WP_004905387.1 erythrose-4-phosphate dehydrogenase -
L3Q80_RS15880 (L3Q80_15870) 3365415..3366578 + 1164 WP_004905385.1 phosphoglycerate kinase -
L3Q80_RS15885 (L3Q80_15875) 3366638..3367714 + 1077 WP_094962157.1 class II fructose-bisphosphate aldolase -
L3Q80_RS15890 (L3Q80_15880) 3367889..3368140 + 252 WP_181489335.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
L3Q80_RS15895 (L3Q80_15885) 3368137..3368427 + 291 WP_140172124.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L3Q80_RS15900 (L3Q80_15890) 3368422..3368775 - 354 WP_232368720.1 DUF4440 domain-containing protein -
L3Q80_RS15905 (L3Q80_15895) 3368775..3369632 - 858 WP_036958581.1 LysR substrate-binding domain-containing protein -
L3Q80_RS15910 (L3Q80_15900) 3369717..3370403 + 687 WP_004905375.1 ankyrin repeat domain-containing protein -
L3Q80_RS15915 (L3Q80_15905) 3370403..3370870 + 468 WP_096864803.1 nucleoside deaminase -
L3Q80_RS15920 (L3Q80_15910) 3370867..3372048 + 1182 WP_096864804.1 cyanate transporter -
L3Q80_RS15925 (L3Q80_15915) 3372145..3373014 + 870 WP_181489340.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11124.23 Da        Isoelectric Point: 10.7261

>T246600 WP_140172124.1 NZ_CP098040:3368137-3368427 [Providencia rettgeri]
MTGFYKVKFRDDAAKEWKKLGATIQKQFAKKLKLLIENPHIPSARLSGLQNCYKIKLKASGYRLVYEVVDNQLIIIVVTV
GKRNRNEVYDIAKKRL

Download         Length: 291 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9312.67 Da        Isoelectric Point: 4.1683

>AT246600 WP_181489335.1 NZ_CP098040:3367889-3368140 [Providencia rettgeri]
MPQVILSDVTASISELKKNPMATVDSGEGFPVAILNRNKTAFYCVPAEIYENLLEQIEDKELIEIVNARKNQKLVDVDLD
SYL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References