Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumA-relB/COG3657-dnstrm_HI1420
Location 2724513..2725096 Replicon chromosome
Accession NZ_CP098040
Organism Providencia rettgeri strain 18004577

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag L3Q80_RS13115 Protein ID WP_096863599.1
Coordinates 2724513..2724815 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag L3Q80_RS13120 Protein ID WP_004265229.1
Coordinates 2724812..2725096 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q80_RS13095 (L3Q80_13085) 2721756..2722202 + 447 WP_006812851.1 phage tail protein -
L3Q80_RS13100 (L3Q80_13090) 2722199..2723308 + 1110 WP_181489095.1 phage late control D family protein -
L3Q80_RS13105 (L3Q80_13095) 2723373..2723591 + 219 WP_119246396.1 ogr/Delta-like zinc finger family protein -
L3Q80_RS13110 (L3Q80_13100) 2723626..2724207 - 582 WP_181489097.1 hypothetical protein -
L3Q80_RS13115 (L3Q80_13105) 2724513..2724815 + 303 WP_096863599.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
L3Q80_RS13120 (L3Q80_13110) 2724812..2725096 + 285 WP_004265229.1 putative addiction module antidote protein Antitoxin
L3Q80_RS13125 (L3Q80_13115) 2725179..2725760 + 582 WP_094961882.1 HutD family protein -
L3Q80_RS13130 (L3Q80_13120) 2725980..2726732 + 753 WP_004907010.1 M48 family metallopeptidase -
L3Q80_RS13135 (L3Q80_13125) 2726970..2727611 + 642 WP_140172874.1 lysophospholipid acyltransferase family protein -
L3Q80_RS13140 (L3Q80_13130) 2727608..2728552 + 945 WP_102140623.1 phosphatidate cytidylyltransferase -
L3Q80_RS13145 (L3Q80_13135) 2728959..2729936 + 978 WP_004265237.1 6-phosphofructokinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2690841..2725096 34255


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-93)

Antitoxin

Uncharacterized protein HI1420

(3-91)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11433.37 Da        Isoelectric Point: 10.0723

>T246598 WP_096863599.1 NZ_CP098040:2724513-2724815 [Providencia rettgeri]
MITVLTTECFDSWIKNLRDIRAKTKILMRIRRLKNGNYGDVQPIGDGFSELRVHEGQGYRVYLKQKNNVIVILLCGGTKA
TQQKDIHKAKLLFGEVEGEL

Download         Length: 303 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10454.13 Da        Isoelectric Point: 4.5983

>AT246598 WP_004265229.1 NZ_CP098040:2724812-2725096 [Providencia rettgeri]
MNTKLKEFDIAEYLNSEEEIQMYLNEILEEGDPSLVLAALGDIAKARNMSQLAKEVGMSREGLYKALSGQGNPTFMTIIK
IVNSLGLKLQFKSI

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References