Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1024252..1024909 Replicon chromosome
Accession NZ_CP098040
Organism Providencia rettgeri strain 18004577

Toxin (Protein)


Gene name cptA Uniprot ID A0A264VM08
Locus tag L3Q80_RS04870 Protein ID WP_036958456.1
Coordinates 1024252..1024662 (-) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D4C097
Locus tag L3Q80_RS04875 Protein ID WP_004261864.1
Coordinates 1024643..1024909 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
L3Q80_RS04850 (L3Q80_04845) 1020145..1021878 - 1734 WP_112307214.1 single-stranded-DNA-specific exonuclease RecJ -
L3Q80_RS04855 (L3Q80_04850) 1021888..1022592 - 705 WP_096863312.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
L3Q80_RS04860 (L3Q80_04855) 1022614..1023516 - 903 WP_004261814.1 site-specific tyrosine recombinase XerD -
L3Q80_RS04865 (L3Q80_04860) 1023634..1024152 + 519 WP_094963000.1 flavodoxin FldB -
L3Q80_RS04870 (L3Q80_04865) 1024252..1024662 - 411 WP_036958456.1 protein YgfX Toxin
L3Q80_RS04875 (L3Q80_04870) 1024643..1024909 - 267 WP_004261864.1 FAD assembly factor SdhE Antitoxin
L3Q80_RS04880 (L3Q80_04875) 1025157..1026140 + 984 WP_181488242.1 tRNA-modifying protein YgfZ -
L3Q80_RS04885 (L3Q80_04880) 1026152..1026772 + 621 WP_004261871.1 HD domain-containing protein -
L3Q80_RS04890 (L3Q80_04885) 1027017..1027913 + 897 WP_181488244.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15568.53 Da        Isoelectric Point: 10.7733

>T246595 WP_036958456.1 NZ_CP098040:c1024662-1024252 [Providencia rettgeri]
VVLWKSNLSISWKTQLFSTCVHGVIGMFLLLAPWSPGNSMIWLPLLVVVVASWAKSQKNISKIKGVAVLVNGNKVQWKKN
EWRILKAPWLTRYGILLTLEALQGKPQKLHLWVAKDALSEENWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10684.24 Da        Isoelectric Point: 4.8942

>AT246595 WP_004261864.1 NZ_CP098040:c1024909-1024643 [Providencia rettgeri]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDDLTTHDKQVFVRLLECADPDLFNWLMNHGRPDDDELFRMIKLIQEKN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A264VM08

Antitoxin

Source ID Structure
AlphaFold DB A0A345M2Q5

References