Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 1329019..1329578 Replicon chromosome
Accession NZ_CP098034
Organism Vibrio alginolyticus strain E110

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NAL94_RS14355 Protein ID WP_069543266.1
Coordinates 1329019..1329297 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A347UR21
Locus tag NAL94_RS14360 Protein ID WP_005398409.1
Coordinates 1329294..1329578 (-) Length 95 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL94_RS14295 (NAL94_14295) 1324636..1325022 + 387 WP_250690222.1 hypothetical protein -
NAL94_RS14300 (NAL94_14300) 1325121..1325462 + 342 WP_053320200.1 SH3 domain-containing protein -
NAL94_RS14305 (NAL94_14305) 1325429..1325569 + 141 WP_080659271.1 DUF3265 domain-containing protein -
NAL94_RS14310 (NAL94_14310) 1325602..1326267 + 666 WP_206225575.1 hypothetical protein -
NAL94_RS14315 (NAL94_14315) 1326372..1326635 + 264 WP_238951979.1 hypothetical protein -
NAL94_RS14320 (NAL94_14320) 1326678..1326884 + 207 WP_238952355.1 GNAT family N-acetyltransferase -
NAL94_RS14325 (NAL94_14325) 1326899..1326961 + 63 WP_079749016.1 DUF3265 domain-containing protein -
NAL94_RS14330 (NAL94_14330) 1327025..1327711 + 687 WP_206225574.1 DUF4145 domain-containing protein -
NAL94_RS14335 (NAL94_14335) 1327693..1327818 + 126 WP_241092770.1 DUF3265 domain-containing protein -
NAL94_RS14340 (NAL94_14340) 1328340..1328429 + 90 WP_206225644.1 DUF3265 domain-containing protein -
NAL94_RS14345 (NAL94_14345) 1328462..1328863 + 402 WP_005377049.1 HIT family protein -
NAL94_RS14350 (NAL94_14350) 1328898..1328990 + 93 WP_080276993.1 DUF3265 domain-containing protein -
NAL94_RS14355 (NAL94_14355) 1329019..1329297 - 279 WP_069543266.1 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family Toxin
NAL94_RS14360 (NAL94_14360) 1329294..1329578 - 285 WP_005398409.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
NAL94_RS14365 (NAL94_14365) 1329655..1329746 + 92 Protein_1186 DUF3265 domain-containing protein -
NAL94_RS14370 (NAL94_14370) 1329783..1330334 + 552 WP_191116430.1 ADP-ribosyltransferase -
NAL94_RS14375 (NAL94_14375) 1330357..1330422 + 66 Protein_1188 DUF3265 domain-containing protein -
NAL94_RS14380 (NAL94_14380) 1330854..1330943 + 90 WP_206225637.1 DUF3265 domain-containing protein -
NAL94_RS14385 (NAL94_14385) 1330968..1331354 - 387 WP_064368483.1 hypothetical protein -
NAL94_RS14390 (NAL94_14390) 1331341..1331667 - 327 WP_020840765.1 hypothetical protein -
NAL94_RS14395 (NAL94_14395) 1331950..1332540 + 591 WP_206225573.1 hypothetical protein -
NAL94_RS14400 (NAL94_14400) 1333783..1334277 + 495 WP_206225572.1 GNAT family N-acetyltransferase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1302066..1402830 100764
- inside Integron - - 1302583..1392918 90335


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 93 a.a.        Molecular weight: 10892.52 Da        Isoelectric Point: 4.1856

>T246589 WP_069543266.1 NZ_CP098034:c1329297-1329019 [Vibrio alginolyticus]
MILWEEESLNDREEIFEFLYDFNPDAAEKTDNLIEAKVENLLEQPLMGVQRDGIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKFPTD

Download         Length: 279 bp


Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11069.40 Da        Isoelectric Point: 9.2167

>AT246589 WP_005398409.1 NZ_CP098034:c1329578-1329294 [Vibrio alginolyticus]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQTAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure
AlphaFold DB A0A347UR21

References