Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3146879..3147510 Replicon chromosome
Accession NZ_CP098030
Organism Serratia ureilytica strain HNU47

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag NAL25_RS15210 Protein ID WP_094142813.1
Coordinates 3146879..3147277 (-) Length 133 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag NAL25_RS15215 Protein ID WP_046896588.1
Coordinates 3147277..3147510 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL25_RS15185 (NAL25_15165) 3142454..3142828 + 375 WP_182264261.1 type II toxin-antitoxin system RelE/ParE family toxin -
NAL25_RS15190 (NAL25_15170) 3142821..3143123 + 303 WP_015378258.1 DNA-binding transcriptional regulator -
NAL25_RS15195 (NAL25_15175) 3143126..3143530 - 405 WP_033643530.1 flagellar protein FlhE -
NAL25_RS15200 (NAL25_15180) 3143530..3145608 - 2079 WP_103085412.1 flagellar biosynthesis protein FlhA -
NAL25_RS15205 (NAL25_15185) 3145601..3146752 - 1152 WP_019452962.1 flagellar biosynthesis protein FlhB -
NAL25_RS15210 (NAL25_15190) 3146879..3147277 - 399 WP_094142813.1 type II toxin-antitoxin system VapC family toxin Toxin
NAL25_RS15215 (NAL25_15195) 3147277..3147510 - 234 WP_046896588.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
NAL25_RS15220 (NAL25_15200) 3147636..3148280 - 645 WP_004934858.1 protein phosphatase CheZ -
NAL25_RS15225 (NAL25_15205) 3148291..3148680 - 390 WP_004934862.1 chemotaxis response regulator CheY -
NAL25_RS15230 (NAL25_15210) 3148783..3149832 - 1050 WP_046896587.1 chemotaxis response regulator protein-glutamate methylesterase -
NAL25_RS15235 (NAL25_15215) 3149832..3150704 - 873 WP_046896586.1 protein-glutamate O-methyltransferase CheR -
NAL25_RS15240 (NAL25_15220) 3150742..3152358 - 1617 WP_046896585.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-45)


Sequences

Toxin        


Download         Length: 133 a.a.        Molecular weight: 14890.05 Da        Isoelectric Point: 8.4955

>T246579 WP_094142813.1 NZ_CP098030:c3147277-3146879 [Serratia ureilytica]
MFSHMLDTNIVIYVIKRRPLEVLEAFNRYAGKMVISSVTYGELVHGVEKSSRPAVNARVVEDFVSRLDILDYGAKAASHY
GNIRAALERQGTPIGVNDLHIAGHARSEGLILVTNNRREFERVEGLRLENWL

Download         Length: 399 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8813.84 Da        Isoelectric Point: 5.0789

>AT246579 WP_046896588.1 NZ_CP098030:c3147510-3147277 [Serratia ureilytica]
MTLGSVFTNNRTQAVRLPAEVRFPDTVSKVTVRVVGKERILAPVENTWDSFFCAENEVSDDFLNERAGQHQREREAF

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References