Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2033460..2033600 Replicon chromosome
Accession NZ_CP098030
Organism Serratia ureilytica strain HNU47

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2033504..2033600 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2033460..2033600 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL25_RS09830 (NAL25_09810) 2028680..2029105 + 426 WP_033652008.1 RNA polymerase-binding protein DksA -
NAL25_RS09835 (NAL25_09815) 2029283..2030236 + 954 WP_046899355.1 prolyl aminopeptidase -
NAL25_RS09840 (NAL25_09820) 2030268..2030498 - 231 WP_193549608.1 DNA polymerase III subunit theta -
NAL25_RS09845 (NAL25_09825) 2030839..2031357 + 519 WP_033642716.1 non-heme ferritin -
NAL25_RS09850 (NAL25_09830) 2031651..2032067 + 417 WP_046899289.1 CopC domain-containing protein YobA -
NAL25_RS09855 (NAL25_09835) 2032070..2032951 + 882 WP_193549607.1 copper homeostasis membrane protein CopD -
NAL25_RS09860 (NAL25_09840) 2033021..2033362 + 342 WP_016928154.1 YebY family protein -
- 2033460..2033600 - 141 - - Antitoxin
- 2033504..2033600 + 97 - - Toxin
NAL25_RS09865 (NAL25_09845) 2033679..2034624 - 946 Protein_1903 tyrosine-type recombinase/integrase -
NAL25_RS09870 (NAL25_09850) 2034687..2035085 + 399 WP_052759986.1 tail assembly chaperone -
NAL25_RS09875 (NAL25_09855) 2035111..2035476 - 366 WP_193549606.1 helix-turn-helix transcriptional regulator -
NAL25_RS09880 (NAL25_09860) 2035580..2036386 - 807 WP_072056116.1 helix-turn-helix transcriptional regulator -
NAL25_RS09885 (NAL25_09865) 2036582..2037046 - 465 WP_072056117.1 VOC family protein -
NAL25_RS09890 (NAL25_09870) 2037062..2037862 - 801 WP_072056118.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - gtrB 2026869..2043735 16866


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 97 bp

>T246575 NZ_CP098030:2033504-2033600 [Serratia ureilytica]
AACAAGCCCTGCATTAAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTAGACCGAATATAGGAATC
GTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 141 bp

>AT246575 NZ_CP098030:c2033600-2033460 [Serratia ureilytica]
AAAAAAAGACCGAATACGATTCCTATATTCGGTCTAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TTAATGCAGGGCTTGTTCAGCCGTGCACTTTAAGAGTAGCCTACCGCGCCAGTTTTGCCAG

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References