Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 184508..184983 Replicon chromosome
Accession NZ_CP098030
Organism Serratia ureilytica strain HNU47

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag NAL25_RS00835 Protein ID WP_094141612.1
Coordinates 184708..184983 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NAL25_RS00830 Protein ID WP_257712226.1
Coordinates 184508..184708 (+) Length 67 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL25_RS00800 (NAL25_00800) 179701..180969 + 1269 WP_038874127.1 glycerol-3-phosphate dehydrogenase subunit GlpB -
NAL25_RS00805 (NAL25_00805) 180966..182165 + 1200 WP_033652425.1 anaerobic glycerol-3-phosphate dehydrogenase subunit GlpC -
NAL25_RS00810 (NAL25_00810) 182200..182763 - 564 WP_025304887.1 DcrB family lipoprotein -
NAL25_RS00815 (NAL25_00815) 182844..183278 - 435 WP_182265655.1 GNAT family N-acetyltransferase -
NAL25_RS00820 (NAL25_00820) 183320..183979 - 660 WP_033652423.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
NAL25_RS00825 (NAL25_00825) 184200..184445 + 246 WP_025304890.1 sulfurtransferase TusA -
NAL25_RS00830 (NAL25_00830) 184508..184708 + 201 WP_257712226.1 stability determinant Antitoxin
NAL25_RS00835 (NAL25_00835) 184708..184983 + 276 WP_094141612.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NAL25_RS00840 (NAL25_00840) 185043..187361 - 2319 WP_182265657.1 zinc/cadmium/mercury/lead-transporting ATPase -
NAL25_RS00845 (NAL25_00845) 188042..189505 + 1464 WP_046898846.1 serralysin family metalloprotease -
NAL25_RS00850 189560..189691 + 132 WP_257712232.1 hypothetical protein -
NAL25_RS00855 (NAL25_00850) 189752..189937 + 186 WP_257712233.1 protease inhibitor Inh/omp19 family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10545.42 Da        Isoelectric Point: 10.9105

>T246569 WP_094141612.1 NZ_CP098030:184708-184983 [Serratia ureilytica]
MLSIEWTRAARQDLAEIVGFIANDNPLAARKMKLLIMEAVIPAASHPRLFRRGRVDGTHEIPLHPNYLLVYQVLETHIRV
LRVLHARRQYP

Download         Length: 276 bp

Antitoxin


Download         Length: 67 a.a.        Molecular weight: 7455.59 Da        Isoelectric Point: 4.2686

>AT246569 WP_257712226.1 NZ_CP098030:184508-184708 [Serratia ureilytica]
MMSILLLPTVAKMENEEHTQGYERWFLEKVQEAMDEPLPGIPHDDVMAEMDAVIAAAEARIKAKQS

Download         Length: 201 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References