Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 62233..62768 Replicon chromosome
Accession NZ_CP098030
Organism Serratia ureilytica strain HNU47

Toxin (Protein)


Gene name relE Uniprot ID A0A086G6D5
Locus tag NAL25_RS00280 Protein ID WP_033631416.1
Coordinates 62493..62768 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag NAL25_RS00275 Protein ID WP_257712075.1
Coordinates 62233..62493 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NAL25_RS00255 (NAL25_00255) 57552..58202 + 651 WP_016929564.1 DcrB-related protein -
NAL25_RS00260 (NAL25_00260) 58243..58848 + 606 WP_182265623.1 glutathione S-transferase -
NAL25_RS00265 (NAL25_00265) 58918..60312 + 1395 WP_182265624.1 L-seryl-tRNA(Sec) selenium transferase -
NAL25_RS00270 (NAL25_00270) 60309..62150 + 1842 WP_193550024.1 selenocysteine-specific translation elongation factor -
NAL25_RS00275 (NAL25_00275) 62233..62493 + 261 WP_257712075.1 ribbon-helix-helix domain-containing protein Antitoxin
NAL25_RS00280 (NAL25_00280) 62493..62768 + 276 WP_033631416.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
NAL25_RS00285 (NAL25_00285) 62948..64195 - 1248 WP_033633516.1 MFS transporter -
NAL25_RS00290 (NAL25_00290) 64413..65405 + 993 WP_033652295.1 acyltransferase -
NAL25_RS00295 (NAL25_00295) 65400..66323 - 924 WP_257712083.1 DJ-1/PfpI family protein -
NAL25_RS00300 (NAL25_00300) 66326..66877 - 552 WP_046898791.1 isochorismatase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10548.30 Da        Isoelectric Point: 10.3377

>T246568 WP_033631416.1 NZ_CP098030:62493-62768 [Serratia ureilytica]
MELKWTSKALSDLARLFEFLALANRTAAANSVKALVAAPKALLDNPRLGERLDEFLPQEVRRILVGRYEIRYQVQPAAIY
VLRIWHTREER

Download         Length: 276 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9696.04 Da        Isoelectric Point: 4.5578

>AT246568 WP_257712075.1 NZ_CP098030:62233-62493 [Serratia ureilytica]
MNKKVITAHVPLPLAEKVDEMAAKLDRSRGWIVKQALAAWLEQEEERRRLTLAALADVEEQNVIDHESVEAWAASLDSDE
PLPVPR

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A086G6D5

Antitoxin

Source ID Structure

References