246541

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 1475471..1476105 Replicon chromosome
Accession NZ_CP097984
Organism Pimelobacter simplex strain N39

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag M0M43_RS07175 Protein ID WP_257753291.1
Coordinates 1475695..1476105 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag M0M43_RS07170 Protein ID WP_215813961.1
Coordinates 1475471..1475698 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M0M43_RS07150 (M0M43_07150) 1471086..1471619 + 534 WP_215813965.1 DNA starvation/stationary phase protection protein -
M0M43_RS07155 (M0M43_07155) 1471663..1472871 + 1209 WP_257753288.1 cytochrome P450 -
M0M43_RS07160 (M0M43_07160) 1472873..1473403 + 531 WP_257753289.1 TetR family transcriptional regulator -
M0M43_RS07165 (M0M43_07165) 1473467..1475434 + 1968 WP_257753290.1 AarF/UbiB family protein -
M0M43_RS07170 (M0M43_07170) 1475471..1475698 + 228 WP_215813961.1 ribbon-helix-helix protein, CopG family Antitoxin
M0M43_RS07175 (M0M43_07175) 1475695..1476105 + 411 WP_257753291.1 PIN domain nuclease Toxin
M0M43_RS07180 (M0M43_07180) 1476095..1478446 - 2352 WP_257753292.1 arylsulfatase -
M0M43_RS07185 (M0M43_07185) 1478458..1479417 - 960 WP_257753293.1 formylglycine-generating enzyme family protein -
M0M43_RS07190 (M0M43_07190) 1479414..1481084 - 1671 WP_257753294.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-122)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-42)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15060.29 Da        Isoelectric Point: 5.6749

>T246541 WP_257753291.1 NZ_CP097984:1475695-1476105 [Pimelobacter simplex]
MTDWLIDKSALVRLAHAAERDEWRERCRRGLVRITSPTLLEAGFSARSADDWQALVAGPPVSWFPVEYLTPAIERRALDV
QRILAARGQHRAPSVPDLLIAATAELAGLVVLHLDKDFELIADVTGQQVERLGLTA

Download         Length: 411 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8594.56 Da        Isoelectric Point: 4.2561

>AT246541 WP_215813961.1 NZ_CP097984:1475471-1475698 [Pimelobacter simplex]
MTDLLIRNVPDEDLRRIDDKARRLGLSRADYFRRLILQEAARGVDDAEPGTDVFARFADLAQDLGDDDVMRDAWS

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References