Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pemIK/PRK09812-MazE
Location 2605779..2606369 Replicon chromosome
Accession NZ_CP097983
Organism Pantoea alhagi strain NX-11

Toxin (Protein)


Gene name pemK Uniprot ID -
Locus tag LQ939_RS12155 Protein ID WP_250650246.1
Coordinates 2605779..2606111 (-) Length 111 a.a.

Antitoxin (Protein)


Gene name pemI Uniprot ID -
Locus tag LQ939_RS12160 Protein ID WP_250650247.1
Coordinates 2606112..2606369 (-) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ939_RS12135 (LQ939_12120) 2601747..2602604 - 858 WP_250650244.1 SDR family oxidoreductase -
LQ939_RS12140 (LQ939_12125) 2602913..2603410 + 498 WP_085071259.1 pyridoxamine 5'-phosphate oxidase family protein -
LQ939_RS12145 (LQ939_12130) 2603542..2604990 - 1449 WP_250650245.1 EmmdR/YeeO family multidrug/toxin efflux MATE transporter -
LQ939_RS12155 (LQ939_12140) 2605779..2606111 - 333 WP_250650246.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
LQ939_RS12160 (LQ939_12145) 2606112..2606369 - 258 WP_250650247.1 antitoxin Antitoxin
LQ939_RS12165 (LQ939_12150) 2606717..2606923 - 207 WP_029570199.1 cell morphology transcriptional regulator XreR2 -
LQ939_RS12170 (LQ939_12155) 2606920..2607381 - 462 WP_250650248.1 hypothetical protein -
LQ939_RS12175 (LQ939_12160) 2607364..2607621 - 258 Protein_2379 ash family protein -
LQ939_RS12180 (LQ939_12165) 2607779..2609041 + 1263 WP_250650249.1 hypothetical protein -
LQ939_RS12185 (LQ939_12170) 2609187..2609600 + 414 WP_250650250.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(3-108)

Antitoxin

Antitoxin PemI-like

(4-84)


Sequences

Toxin        


Download         Length: 111 a.a.        Molecular weight: 11903.92 Da        Isoelectric Point: 10.5834

>T246540 WP_250650246.1 NZ_CP097983:c2606111-2605779 [Pantoea alhagi]
MDRGEIWLVSLDPIADHEQSGKRPVLIVSKASFNKLTRLPVVVPVTSGGNFARAAGFTVSLAGAGIKTTGVIRCDQPRTI
DMVARNGKRLERIPESILNEVLARLEAILI

Download         Length: 333 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9412.98 Da        Isoelectric Point: 4.6258

>AT246540 WP_250650247.1 NZ_CP097983:c2606369-2606112 [Pantoea alhagi]
MYTTRLKKVGGSIMLAVPPAVLKTLALSTDSEVGMTIEKGCLIIEPQKRPRYSLEELLAQCDPHAEMSEEDREWIDAPAV
GKEIL

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References