Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 1634995..1635584 Replicon chromosome
Accession NC_013959
Organism Sideroxydans lithotrophicus ES-1

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag SLIT_RS15630 Protein ID WP_013029747.1
Coordinates 1635294..1635584 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag SLIT_RS08080 Protein ID WP_013029746.1
Coordinates 1634995..1635285 (-) Length 97 a.a.

Genomic Context

SLIT_RS08050SLIT_RS08055SLIT_RS08060SLIT_RS08065SLIT_RS15205SLIT_RS08075SLIT_RS08080SLIT_RS15630SLIT_RS08085SLIT_RS08090SLIT_RS08095SLIT_RS08100
Location: 1630054..1630806 (753 bp)
Type: Others
Protein ID: WP_013029740.1
Location: 1630803..1631342 (540 bp)
Type: Others
Protein ID: WP_013029741.1
Location: 1631436..1632923 (1488 bp)
Type: Others
Protein ID: WP_013029742.1
Location: 1632923..1633384 (462 bp)
Type: Others
Protein ID: WP_013029743.1
Location: 1633550..1634392 (843 bp)
Type: Others
Protein ID: WP_013029744.1
Location: 1634644..1634874 (231 bp)
Type: Others
Protein ID: WP_013029745.1
Location: 1634995..1635285 (291 bp)
Type: Antitoxin
Protein ID: WP_013029746.1
Location: 1635294..1635584 (291 bp)
Type: Toxin
Protein ID: WP_013029747.1
Location: 1635782..1637551 (1770 bp)
Type: Others
Protein ID: WP_013029748.1
Location: 1637562..1637999 (438 bp)
Type: Others
Protein ID: WP_013029749.1
Location: 1638004..1639266 (1263 bp)
Type: Others
Protein ID: WP_013029750.1
Location: 1639282..1639941 (660 bp)
Type: Others
Protein ID: WP_013029751.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
SLIT_RS080501630054..1630806+753WP_013029740.1(2Fe-2S)-binding protein-
SLIT_RS080551630803..1631342+540WP_013029741.1NADP oxidoreductase-
SLIT_RS080601631436..1632923+1488WP_013029742.1Ni/Fe hydrogenase subunit alpha-
SLIT_RS080651632923..1633384+462WP_013029743.1hydrogenase maturation protease-
SLIT_RS152051633550..1634392-843WP_013029744.1DUF1311 domain-containing protein-
SLIT_RS080751634644..1634874-231WP_013029745.1hypothetical protein-
SLIT_RS080801634995..1635285-291WP_013029746.1putative addiction module antidote proteinAntitoxin
SLIT_RS156301635294..1635584-291WP_013029747.1type II toxin-antitoxin system RelE/ParE family toxinToxin
SLIT_RS080851635782..1637551-1770WP_013029748.1nickel-dependent hydrogenase large subunit-
SLIT_RS080901637562..1637999-438WP_013029749.1hypothetical protein-
SLIT_RS080951638004..1639266-1263WP_013029750.1(Fe-S)-binding protein-
SLIT_RS081001639282..1639941-660WP_013029751.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-96)

Antitoxin

Cro/C1-type helix-turn-helix domain

(40-92)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 10848.52 Da        Isoelectric Point: 9.8310

>T24654 WP_013029747.1 NC_013959:c1635584-1635294 [Sideroxydans lithotrophicus ES-1]
MIEIRKTAEYAKWIDDLRDPQARTRILVRIERLRSGNPGDAKPVGSGVSELRIDYGPGYRVYFIKHGEILIVLLAGGDKR
TQEADIKTALRLAENL

Download         Length: 291 bp

>T24654 NC_013959:c1635584-1635294 [Sideroxydans lithotrophicus ES-1]
ATGATTGAAATTCGCAAAACAGCCGAATACGCAAAATGGATTGACGATCTACGAGACCCGCAGGCACGAACGAGAATTTT
AGTTCGAATTGAAAGGTTACGATCTGGCAATCCAGGAGATGCAAAACCAGTTGGATCTGGGGTGTCTGAATTGAGGATTG
ATTACGGCCCTGGTTACAGAGTTTATTTCATTAAACATGGTGAGATATTGATTGTTCTCCTAGCGGGTGGAGATAAACGA
ACTCAAGAAGCAGACATTAAAACTGCTTTGCGCCTTGCGGAGAATTTGTAG

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10362.81 Da        Isoelectric Point: 5.6981

>AT24654 WP_013029746.1 NC_013959:c1635285-1634995 [Sideroxydans lithotrophicus ES-1]
MNKTQTSSYDVAEHLRTPEEMALYLDACIEEADGDAAFIAKALGDIARARGMSQVAKDTGLSRESLYKALSGERAPTFDT
ILKVTKALGMKLHASV

Download         Length: 291 bp

>AT24654 NC_013959:c1635285-1634995 [Sideroxydans lithotrophicus ES-1]
ATGAATAAAACTCAAACTTCAAGTTACGATGTTGCAGAACATCTCCGTACGCCAGAAGAAATGGCACTCTACCTTGATGC
ATGCATCGAAGAGGCTGATGGTGATGCCGCATTCATCGCAAAAGCTCTTGGTGATATAGCCCGCGCTCGTGGTATGTCAC
AGGTCGCAAAAGATACTGGCCTTTCACGAGAGAGTTTGTACAAGGCTCTTTCAGGCGAAAGAGCGCCAACCTTTGACACT
ATTCTAAAGGTAACGAAGGCCCTTGGCATGAAACTTCACGCCAGCGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References