246534

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1248118..1248744 Replicon chromosome
Accession NZ_CP097983
Organism Pantoea alhagi strain NX-11

Toxin (Protein)


Gene name Hha Uniprot ID A0A2K1QC31
Locus tag LQ939_RS05690 Protein ID WP_071883698.1
Coordinates 1248118..1248336 (-) Length 73 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID -
Locus tag LQ939_RS05695 Protein ID WP_085067696.1
Coordinates 1248364..1248744 (-) Length 127 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQ939_RS05660 (LQ939_05650) 1244089..1244427 + 339 WP_007886947.1 P-II family nitrogen regulator -
LQ939_RS05665 (LQ939_05655) 1244463..1245747 + 1285 Protein_1112 ammonium transporter AmtB -
LQ939_RS05670 (LQ939_05660) 1245802..1246662 - 861 WP_250652062.1 acyl-CoA thioesterase II -
LQ939_RS05675 (LQ939_05665) 1246878..1247432 + 555 WP_250652063.1 YbaY family lipoprotein -
LQ939_RS05680 (LQ939_05670) 1247463..1247771 - 309 WP_085067697.1 MGMT family protein -
LQ939_RS05690 (LQ939_05680) 1248118..1248336 - 219 WP_071883698.1 HHA domain-containing protein Toxin
LQ939_RS05695 (LQ939_05685) 1248364..1248744 - 381 WP_085067696.1 Hha toxicity modulator TomB Antitoxin
LQ939_RS05700 (LQ939_05690) 1248893..1249237 - 345 WP_085067695.1 hypothetical protein -
LQ939_RS05705 (LQ939_05695) 1249590..1249730 - 141 WP_085067694.1 type B 50S ribosomal protein L36 -
LQ939_RS05710 (LQ939_05700) 1249746..1250003 - 258 WP_085067693.1 type B 50S ribosomal protein L31 -
LQ939_RS05715 (LQ939_05705) 1250187..1253336 - 3150 WP_250652064.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(13-69)

Antitoxin

Biofilm formation regulator YbaJ

(1-114)


Sequences

Toxin        


Download         Length: 73 a.a.        Molecular weight: 8701.16 Da        Isoelectric Point: 8.8578

>T246534 WP_071883698.1 NZ_CP097983:c1248336-1248118 [Pantoea alhagi]
MTEKIMTKTDYLMRLRRCRSIDTLERVIEKNKYELPDDELAVFYSAADHRLAELTMNKLYDKVPVSVWKYVR

Download         Length: 219 bp

Antitoxin


Download         Length: 127 a.a.        Molecular weight: 14727.33 Da        Isoelectric Point: 4.2930

>AT246534 WP_085067696.1 NZ_CP097983:c1248744-1248364 [Pantoea alhagi]
MDEYSPKRHDIAQLNFLCENLYDESMATLGDSHHGWVNDPTSASNLQLNDLIEHIASFTMNYKIKHAEDEDLIVQIDDYL
DDTFMLFSNYGINVQDLQRWQRSARRLFNLFAEECAQLPLQPSHSF

Download         Length: 381 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2K1QC31

Antitoxin

Source ID Structure

References