Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higB-toxA/Tad-couple_hipB
Location 2964471..2965144 Replicon chromosome
Accession NZ_CP097897
Organism Acetobacterium wieringae strain CH1

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag CHL1_RS14530 Protein ID WP_250933628.1
Coordinates 2964779..2965144 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name toxA Uniprot ID -
Locus tag CHL1_RS14525 Protein ID WP_250933626.1
Coordinates 2964471..2964782 (-) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CHL1_RS14515 (CHL1_002901) 2963009..2963635 - 627 WP_250933622.1 hypothetical protein -
CHL1_RS14520 (CHL1_002902) 2963902..2964327 + 426 WP_250933623.1 pyridoxamine 5'-phosphate oxidase family protein -
CHL1_RS14525 (CHL1_002903) 2964471..2964782 - 312 WP_250933626.1 helix-turn-helix transcriptional regulator Antitoxin
CHL1_RS14530 (CHL1_002904) 2964779..2965144 - 366 WP_250933628.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CHL1_RS14535 (CHL1_002905) 2965284..2966555 - 1272 WP_250933629.1 nickel-dependent lactate racemase -
CHL1_RS14540 (CHL1_002906) 2966791..2968329 - 1539 WP_250933631.1 L-lactate permease -
CHL1_RS14545 (CHL1_002907) 2968338..2969738 - 1401 WP_250933633.1 FAD-binding oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(39-111)

Antitoxin

Cro/C1-type helix-turn-helix domain

(40-93)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 14601.78 Da        Isoelectric Point: 9.9994

>T246530 WP_250933628.1 NZ_CP097897:c2965144-2964779 [Acetobacterium wieringae]
MYEVIFYKDAKGNEPIREYLTSLKTKASSSKQNRVKFIKITSYIRSLQEYGTRIGNPTVKHIDGDIWELRPLSDRIFFFY
WQDDTFVLLHYFHKKSQKIPRKEIEKAINNMNDFKERVCQQ

Download         Length: 366 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11587.40 Da        Isoelectric Point: 4.4569

>AT246530 WP_250933626.1 NZ_CP097897:c2964782-2964471 [Acetobacterium wieringae]
MSIKIGNEEFTEFNDLYNDSDFLSDSERAEIEFEVALIGKLIEAREQCGMSQKQLADLTGLKQPAIARLENLKAIPKIDT
LFKLLDPLGYTLAIVPKEKTIVK

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References