246527

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 3646192..3646745 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name ccdB Uniprot ID A0A1V2R684
Locus tag M9782_RS16005 Protein ID WP_039360030.1
Coordinates 3646192..3646506 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID A0A1V2R6A1
Locus tag M9782_RS16010 Protein ID WP_039360032.1
Coordinates 3646509..3646745 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS15985 (M9782_15990) 3641502..3642518 + 1017 WP_275070822.1 P-type DNA transfer ATPase VirB11 -
M9782_RS15990 (M9782_15995) 3642562..3642864 + 303 WP_275070823.1 conjugal transfer protein -
M9782_RS15995 (M9782_16000) 3643661..3645397 + 1737 WP_275070824.1 type IV secretory system conjugative DNA transfer family protein -
M9782_RS16000 (M9782_16005) 3645406..3646158 + 753 WP_275070825.1 MobC family replication-relaxation protein -
M9782_RS16005 (M9782_16010) 3646192..3646506 - 315 WP_039360030.1 CcdB family protein Toxin
M9782_RS16010 (M9782_16015) 3646509..3646745 - 237 WP_039360032.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
M9782_RS16015 (M9782_16020) 3647073..3647990 - 918 WP_275070826.1 zincin-like metallopeptidase domain-containing protein -
M9782_RS16020 (M9782_16025) 3648602..3648829 - 228 WP_039360037.1 hypothetical protein -
M9782_RS16025 (M9782_16030) 3649155..3649373 - 219 WP_151242679.1 cold shock domain-containing protein -
M9782_RS16030 (M9782_16035) 3649656..3649868 + 213 WP_151242680.1 cold shock-like protein CspF -
M9782_RS16035 (M9782_16040) 3649950..3650108 + 159 WP_222431663.1 YnfU family zinc-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 3619532..3664562 45030


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11535.48 Da        Isoelectric Point: 7.9859

>T246527 WP_039360030.1 NZ_CP097896:c3646506-3646192 [Pectobacterium actinidiae]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRTQVKAAIDFLIDGF

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8973.05 Da        Isoelectric Point: 6.4610

>AT246527 WP_039360032.1 NZ_CP097896:c3646745-3646509 [Pectobacterium actinidiae]
MTAKPRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRYHEAKKWQEENREALAALNRFHDEQGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1V2R684

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R6A1

References