Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2398831..2399741 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag M9782_RS10245 Protein ID WP_275072310.1
Coordinates 2399271..2399741 (+) Length 157 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID A0A1V2R4X7
Locus tag M9782_RS10240 Protein ID WP_039357407.1
Coordinates 2398831..2399274 (+) Length 148 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS10220 (M9782_10220) 2394226..2395257 + 1032 WP_275072307.1 iron ABC transporter permease -
M9782_RS10225 (M9782_10225) 2395270..2396121 + 852 WP_275072308.1 ABC transporter ATP-binding protein -
M9782_RS10230 (M9782_10230) 2396111..2396920 + 810 WP_039506867.1 IucA/IucC family C-terminal-domain containing protein -
M9782_RS10235 (M9782_10235) 2397218..2398654 + 1437 WP_275072309.1 ATP-dependent RNA helicase RhlE -
M9782_RS10240 (M9782_10240) 2398831..2399274 + 444 WP_039357407.1 DUF2384 domain-containing protein Antitoxin
M9782_RS10245 (M9782_10245) 2399271..2399741 + 471 WP_275072310.1 RES family NAD+ phosphorylase Toxin
M9782_RS10250 (M9782_10250) 2399842..2401071 - 1230 WP_275072311.1 peptidase T -
M9782_RS10255 (M9782_10255) 2401212..2402807 + 1596 WP_275072312.1 ABC transporter substrate-binding protein -
M9782_RS10260 (M9782_10260) 2402858..2403529 - 672 WP_275072313.1 epoxyqueuosine reductase QueH -
M9782_RS10265 (M9782_10265) 2403743..2404675 + 933 WP_039357417.1 tRNA dihydrouridine(16) synthase DusC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-147)

Antitoxin

Antitoxin Xre-like, helix-turn-helix domain

(30-89)


Sequences

Toxin        


Download         Length: 157 a.a.        Molecular weight: 17804.24 Da        Isoelectric Point: 4.6251

>T246526 WP_275072310.1 NZ_CP097896:2399271-2399741 [Pectobacterium actinidiae]
MILYRLTKTKYLSTAWTGYGAKEAGGRWNSVGTSMVYVSETASLTMLETLVHLHAAQILDYYTLMRIDVPEDQIQSANMD
ELPDNWAAEEAPPDLAVYGDAWIFTQSSIALRVPSALSPVEYNYLLNPEHPDFYGIIQRVEVIPFQFDRRLKPERK

Download         Length: 471 bp

Antitoxin


Download         Length: 148 a.a.        Molecular weight: 16449.80 Da        Isoelectric Point: 9.6203

>AT246526 WP_039357407.1 NZ_CP097896:2398831-2399274 [Pectobacterium actinidiae]
MKTFSLSTTQTRPPRLWQVAGLHHSDGVALLGQIREGLEGNVANLIADWAKITQSDLRKMSGIPSTTFSRSVKARFNADQ
SERLVRIIRVIDRAVELFEGDKDDAQKWLNEPNRALGGKIPTELMVSETGAYEVMKLLTRLEHGVYS

Download         Length: 444 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R4X7

References