Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 2072437..2073236 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name hepT Uniprot ID -
Locus tag M9782_RS09065 Protein ID WP_275072171.1
Coordinates 2072437..2072856 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID A0A094SX92
Locus tag M9782_RS09070 Protein ID WP_039473810.1
Coordinates 2072853..2073236 (-) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS09045 (M9782_09045) 2067549..2068190 + 642 WP_010281304.1 uridine kinase -
M9782_RS09050 (M9782_09050) 2068298..2068879 + 582 WP_005974037.1 dCTP deaminase -
M9782_RS09055 (M9782_09055) 2068942..2070777 + 1836 WP_275072169.1 outer membrane assembly protein AsmA -
M9782_RS09060 (M9782_09060) 2071041..2072393 + 1353 WP_275072170.1 anaerobic C4-dicarboxylate transporter DcuC -
M9782_RS09065 (M9782_09065) 2072437..2072856 - 420 WP_275072171.1 DUF86 domain-containing protein Toxin
M9782_RS09070 (M9782_09070) 2072853..2073236 - 384 WP_039473810.1 nucleotidyltransferase domain-containing protein Antitoxin
M9782_RS09075 (M9782_09075) 2073350..2074936 - 1587 WP_275072172.1 TerC family protein -
M9782_RS09080 (M9782_09080) 2075669..2076766 + 1098 WP_275072173.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
M9782_RS09085 (M9782_09085) 2076884..2078020 + 1137 WP_039356693.1 polysaccharide export protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(4-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16078.45 Da        Isoelectric Point: 6.9682

>T246525 WP_275072171.1 NZ_CP097896:c2072856-2072437 [Pectobacterium actinidiae]
MIDILLNKSTTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITIDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFEHFIKQIARYSDSQHL

Download         Length: 420 bp

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14372.57 Da        Isoelectric Point: 4.7463

>AT246525 WP_039473810.1 NZ_CP097896:c2073236-2072853 [Pectobacterium actinidiae]
MFDKIVLTLKKQMPDIKIIYLFGSQATGNARADSDIDIAIMATRALDPVERWELSNQLAKEVGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAETAAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Download         Length: 384 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A094SX92

References