Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1815535..1816161 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag M9782_RS07905 Protein ID WP_005976087.1
Coordinates 1815535..1815738 (-) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID C6DB73
Locus tag M9782_RS07910 Protein ID WP_005976089.1
Coordinates 1815793..1816161 (-) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS07875 (M9782_07875) 1810995..1811333 + 339 WP_002208627.1 P-II family nitrogen regulator -
M9782_RS07880 (M9782_07880) 1811373..1812659 + 1287 WP_039356190.1 ammonium transporter AmtB -
M9782_RS07885 (M9782_07885) 1812795..1813658 - 864 WP_039356193.1 acyl-CoA thioesterase II -
M9782_RS07890 (M9782_07890) 1813872..1814453 + 582 WP_039356196.1 YbaY family lipoprotein -
M9782_RS07895 (M9782_07895) 1814473..1814793 - 321 WP_039356201.1 MGMT family protein -
M9782_RS07905 (M9782_07905) 1815535..1815738 - 204 WP_005976087.1 HHA domain-containing protein Toxin
M9782_RS07910 (M9782_07910) 1815793..1816161 - 369 WP_005976089.1 Hha toxicity modulator TomB Antitoxin
M9782_RS07915 (M9782_07915) 1816758..1816901 - 144 WP_005976091.1 type B 50S ribosomal protein L36 -
M9782_RS07920 (M9782_07920) 1816919..1817167 - 249 WP_039356204.1 type B 50S ribosomal protein L31 -
M9782_RS07925 (M9782_07925) 1817396..1820524 - 3129 WP_039356206.1 efflux RND transporter permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T246524 WP_005976087.1 NZ_CP097896:c1815738-1815535 [Pectobacterium actinidiae]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14032.77 Da        Isoelectric Point: 4.4787

>AT246524 WP_005976089.1 NZ_CP097896:c1816161-1815793 [Pectobacterium actinidiae]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENVCTPAKT

Download         Length: 369 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z3G5

References