Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1586235..1586761 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag M9782_RS06965 Protein ID WP_275071993.1
Coordinates 1586235..1586540 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag M9782_RS06970 Protein ID WP_275071994.1
Coordinates 1586543..1586761 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS06935 (M9782_06935) 1581267..1581560 + 294 WP_275071987.1 DUF1778 domain-containing protein -
M9782_RS06940 (M9782_06940) 1581557..1582051 + 495 WP_275071988.1 GNAT family N-acetyltransferase -
M9782_RS06945 (M9782_06945) 1582207..1582755 + 549 WP_275071989.1 3'-5' exonuclease -
M9782_RS06950 (M9782_06950) 1582864..1583964 - 1101 WP_275071990.1 SAVED domain-containing protein -
M9782_RS06955 (M9782_06955) 1584004..1584531 - 528 WP_275071991.1 hypothetical protein -
M9782_RS06960 (M9782_06960) 1584538..1585818 - 1281 WP_275071992.1 nucleotidyltransferase -
M9782_RS06965 (M9782_06965) 1586235..1586540 - 306 WP_275071993.1 type II toxin-antitoxin system toxin CcdB Toxin
M9782_RS06970 (M9782_06970) 1586543..1586761 - 219 WP_275071994.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
M9782_RS06975 (M9782_06975) 1586820..1587563 - 744 WP_275071995.1 MobC family replication-relaxation protein -
M9782_RS06980 (M9782_06980) 1588475..1588816 - 342 WP_275071996.1 hypothetical protein -
M9782_RS06985 (M9782_06985) 1588957..1589127 + 171 WP_275071997.1 hypothetical protein -
M9782_RS06990 (M9782_06990) 1589269..1590528 - 1260 WP_275071998.1 integrase arm-type DNA-binding domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1580246..1590528 10282


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11747.62 Da        Isoelectric Point: 4.8500

>T246523 WP_275071993.1 NZ_CP097896:c1586540-1586235 [Pectobacterium actinidiae]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMVIPLIESHHLSEKVNKTLFPLIRVDGEDYRLMTTELSSVPVEVIGEVI
ADLGDYADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8176.13 Da        Isoelectric Point: 6.4600

>AT246523 WP_275071994.1 NZ_CP097896:c1586761-1586543 [Pectobacterium actinidiae]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDAIGKEARRIRAEEWKKENCEGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References