Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 1581267..1582051 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag M9782_RS06940 Protein ID WP_275071988.1
Coordinates 1581557..1582051 (+) Length 165 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag M9782_RS06935 Protein ID WP_275071987.1
Coordinates 1581267..1581560 (+) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS06915 (M9782_06915) 1576471..1578033 - 1563 WP_275071986.1 class I adenylate-forming enzyme family protein -
M9782_RS06920 (M9782_06920) 1578293..1579261 + 969 WP_039355779.1 LysR family transcriptional regulator -
M9782_RS06925 (M9782_06925) 1579527..1579811 + 285 Protein_1343 DNA helicase -
M9782_RS06930 (M9782_06930) 1579884..1580995 + 1112 WP_130621652.1 IS3 family transposase -
M9782_RS06935 (M9782_06935) 1581267..1581560 + 294 WP_275071987.1 DUF1778 domain-containing protein Antitoxin
M9782_RS06940 (M9782_06940) 1581557..1582051 + 495 WP_275071988.1 GNAT family N-acetyltransferase Toxin
M9782_RS06945 (M9782_06945) 1582207..1582755 + 549 WP_275071989.1 3'-5' exonuclease -
M9782_RS06950 (M9782_06950) 1582864..1583964 - 1101 WP_275071990.1 SAVED domain-containing protein -
M9782_RS06955 (M9782_06955) 1584004..1584531 - 528 WP_275071991.1 hypothetical protein -
M9782_RS06960 (M9782_06960) 1584538..1585818 - 1281 WP_275071992.1 nucleotidyltransferase -
M9782_RS06965 (M9782_06965) 1586235..1586540 - 306 WP_275071993.1 type II toxin-antitoxin system toxin CcdB -
M9782_RS06970 (M9782_06970) 1586543..1586761 - 219 WP_275071994.1 type II toxin-antitoxin system antitoxin CcdA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1580246..1590528 10282


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(76-143)

Antitoxin

Vibrio phage ICP1, Orf50

(14-88)


Sequences

Toxin        


Download         Length: 165 a.a.        Molecular weight: 17594.51 Da        Isoelectric Point: 7.8046

>T246522 WP_275071988.1 NZ_CP097896:1581557-1582051 [Pectobacterium actinidiae]
MISAPEPLHAEHVLSSFCCGVESMDNWLKLRAMKNQVTGASRTFVSCDGAKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDKSLHGQGVGRALVRDAGLRVIQVADTIGIRGMLVHALSDEAREFYLRVGFEPSPIDPMMLMVTLGDLVG
SLSI

Download         Length: 495 bp

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10872.44 Da        Isoelectric Point: 10.1968

>AT246522 WP_275071987.1 NZ_CP097896:1581267-1581560 [Pectobacterium actinidiae]
MPVTNSASVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQAPSPN
AALRKTMQTPAPWEQKK

Download         Length: 294 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References