Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1301223..1301883 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name cptA Uniprot ID A0A1V2R8T2
Locus tag M9782_RS05795 Protein ID WP_039355399.1
Coordinates 1301470..1301883 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1V2R9A9
Locus tag M9782_RS05790 Protein ID WP_039355397.1
Coordinates 1301223..1301489 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS05770 (M9782_05770) 1297355..1298359 - 1005 WP_275071868.1 substrate-binding domain-containing protein -
M9782_RS05775 (M9782_05775) 1298414..1299022 - 609 WP_039355390.1 HD domain-containing protein -
M9782_RS05780 (M9782_05780) 1299284..1299931 + 648 WP_275071869.1 hemolysin III family protein -
M9782_RS05785 (M9782_05785) 1299986..1300987 - 1002 WP_151242992.1 tRNA-modifying protein YgfZ -
M9782_RS05790 (M9782_05790) 1301223..1301489 + 267 WP_039355397.1 FAD assembly factor SdhE Antitoxin
M9782_RS05795 (M9782_05795) 1301470..1301883 + 414 WP_039355399.1 protein YgfX Toxin
M9782_RS05800 (M9782_05800) 1301951..1302886 + 936 WP_275071870.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
M9782_RS05805 (M9782_05805) 1302952..1303275 - 324 WP_275071871.1 hypothetical protein -
M9782_RS05810 (M9782_05810) 1303304..1303822 - 519 WP_039355405.1 flavodoxin FldB -
M9782_RS05815 (M9782_05815) 1304164..1304550 - 387 WP_039355407.1 thioesterase family protein -
M9782_RS05820 (M9782_05820) 1304737..1306065 - 1329 WP_039355408.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16283.21 Da        Isoelectric Point: 10.5525

>T246520 WP_039355399.1 NZ_CP097896:1301470-1301883 [Pectobacterium actinidiae]
VAQWQCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Download         Length: 414 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10506.99 Da        Isoelectric Point: 6.2223

>AT246520 WP_039355397.1 NZ_CP097896:1301223-1301489 [Pectobacterium actinidiae]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1V2R8T2

Antitoxin

Source ID Structure
AlphaFold DB A0A1V2R9A9

References