Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1137371..1137897 Replicon chromosome
Accession NZ_CP097896
Organism Pectobacterium actinidiae strain GX-Pa1

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag M9782_RS05035 Protein ID WP_275071809.1
Coordinates 1137371..1137676 (-) Length 102 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag M9782_RS05040 Protein ID WP_275071810.1
Coordinates 1137679..1137897 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9782_RS05025 (M9782_05025) 1134026..1135975 + 1950 WP_275071807.1 helicase-related protein -
M9782_RS05030 (M9782_05030) 1135977..1137236 + 1260 WP_275071808.1 GIY-YIG nuclease family protein -
M9782_RS05035 (M9782_05035) 1137371..1137676 - 306 WP_275071809.1 type II toxin-antitoxin system toxin CcdB Toxin
M9782_RS05040 (M9782_05040) 1137679..1137897 - 219 WP_275071810.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
M9782_RS05045 (M9782_05045) 1137956..1138699 - 744 WP_275071811.1 MobC family replication-relaxation protein -
M9782_RS05050 (M9782_05050) 1139611..1139952 - 342 WP_038917757.1 hypothetical protein -
M9782_RS05055 (M9782_05055) 1140093..1140263 + 171 WP_162847981.1 hypothetical protein -
M9782_RS05060 (M9782_05060) 1140404..1141663 - 1260 WP_275071812.1 integrase arm-type DNA-binding domain-containing protein -
M9782_RS05070 (M9782_05070) 1142027..1142602 - 576 WP_010301517.1 transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1124675..1141840 17165


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-100)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11634.60 Da        Isoelectric Point: 4.6508

>T246519 WP_275071809.1 NZ_CP097896:c1137676-1137371 [Pectobacterium actinidiae]
MQFIVYQYKRASHYKMFVDVQSDIVETPKRRMAIPLIEAHHLSEKVNKMLFPLICIDGEDYRLMTTELSSVPVEVIGEVI
ADLGDCADEIKDAINLMFWGI

Download         Length: 306 bp

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8257.23 Da        Isoelectric Point: 7.2041

>AT246519 WP_275071810.1 NZ_CP097896:c1137897-1137679 [Pectobacterium actinidiae]
MKHRVSVTVDKDNYQVLSAAGVNISGLVNDVIGKEARRIRAEEWKKENREGMEEVARFIAQHGSFADENRNW

Download         Length: 219 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References