Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 871469..871872 Replicon chromosome
Accession NZ_CP097885
Organism Peptoniphilus sp. SAHP1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag M9426_RS04165 Protein ID WP_250342558.1
Coordinates 871469..871717 (-) Length 83 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag M9426_RS04170 Protein ID WP_250342559.1
Coordinates 871714..871872 (-) Length 53 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
M9426_RS04135 (M9426_04130) 866589..867737 - 1149 WP_250342552.1 cation diffusion facilitator family transporter -
M9426_RS04140 (M9426_04135) 867931..868497 - 567 WP_250342553.1 DJ-1/PfpI family protein -
M9426_RS04145 (M9426_04140) 868507..869271 - 765 WP_250342554.1 pyrroline-5-carboxylate reductase -
M9426_RS04150 (M9426_04145) 869350..869910 + 561 WP_250342555.1 chromate transporter -
M9426_RS04155 (M9426_04150) 869903..870460 + 558 WP_250342556.1 chromate transporter -
M9426_RS04160 (M9426_04155) 870582..871364 - 783 WP_250342557.1 ADP-ribosylglycohydrolase family protein -
M9426_RS04165 (M9426_04160) 871469..871717 - 249 WP_250342558.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
M9426_RS04170 (M9426_04165) 871714..871872 - 159 WP_250342559.1 DUF6290 family protein Antitoxin
M9426_RS04175 (M9426_04170) 871996..873261 - 1266 WP_250342560.1 erythromycin esterase family protein -
M9426_RS04180 (M9426_04175) 873346..874317 - 972 WP_060799874.1 phosphate acetyltransferase -
M9426_RS04185 (M9426_04180) 874373..875347 - 975 WP_250342561.1 dihydropteroate synthase -
M9426_RS04190 (M9426_04185) 875443..876438 - 996 WP_250342562.1 MBL fold metallo-hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-77)

Antitoxin

Protein of unknown function DUF6290

(2-50)


Sequences

Toxin        


Download         Length: 83 a.a.        Molecular weight: 9793.49 Da        Isoelectric Point: 10.9290

>T246507 WP_250342558.1 NZ_CP097885:c871717-871469 [Peptoniphilus sp. SAHP1]
MTYQVRTTKKFDKSFKKLDRQSQKLIKNWMDGNLIGCQNARLYGKALTGNFKGVWRYRIGAYRLLAKIDDDKLIIFFIDR
RN

Download         Length: 249 bp

Antitoxin


Download         Length: 53 a.a.        Molecular weight: 6219.06 Da        Isoelectric Point: 4.0183

>AT246507 WP_250342559.1 NZ_CP097885:c871872-871714 [Peptoniphilus sp. SAHP1]
MGEPLSTLFKRLMEEKLEDEFDMKVAEDFLEREARGEVETRPIEDLFKELDL

Download         Length: 159 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References